A 10-week experiment was conducted to evaluate the combined effect of enzyme complex + yeast (Maxigrain®, MXG®) supplementation of sun-dried yam peel meal (YPM) based diet of laying Japanese quails (Coturnix coturnix japonica) on performance and egg quality. A total of 240, seven-weeks old quails were distributed in a completely randomize design with four dietary treatments and five replicates of 12 quails each. Diet 1 served as the control diet without YPM while diet 2, 3, and 4 contained 25, 50, and 75% YPM with MXG® supplementation (1g per kg), respectively. MXG® supplementation in YPM diets improved (p < 0.05) egg mass and feed conversion per egg. Increasing levels of YPM with MXG® supplementation did not show any effect (p > 0.05) on internal and external egg quality attributes except for eggshell weight and thickness which was higher (p < 0.05) in quails fed 75% YPM diet. It was concluded, therefore, that the utilization of YPM as an alternative dietary ingredient with MXG® supplementation can be tolerated in the diets of laying Japanese quails up to 75% inclusion level without any negative effect on productive and egg quality performance.