Zero contrast optical coherence tomography–guided percutaneous coronary intervention for in-stent restenosis of the saphenous vein graft using a non-contrast flush medium

Vasu, Nandhakumar; Subban, Vijayakumar; Mullasari, S. Ajit

doi:10.1016/j.ihj.2018.11.001

Cited by 4 publications

(1 citation statement)

References 9 publications

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“…While this strategy has been primarily used IVUS, recently, zero contrast PCI has also been reported with OCT guidance using low molecular weight dextran. The additional advantage with OCT guided zero contrast PCI, is the feasibility of co-registration of fluoroscopic images with OCT longitudinal and cross-sectional images (88,89).…”

Section: Minimal or Zero Contrast Angioplastymentioning

confidence: 99%

Optical coherence tomography: fundamentals and clinical utility

Subban

Raffel²

2020

Cardiovasc Diagn Ther

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Although coronary angiography is the standard method employed to assess the severity of coronary artery disease and to guide treatment strategies, it provides only 2D image of the intravascular lesions. In contrast, intravascular imaging modalities such as optical coherence tomography (OCT) produce cross-sectional images of the coronary arteries at a far greater spatial resolution, capable of accurately determining vessel size as well as plaque morphology, eliminating many of the disadvantages inherent to angiography. This review will discuss the role of OCT in the catherization laboratory for the assessment and management of coronary disease.

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Section: Minimal or Zero Contrast Angioplastymentioning

confidence: 99%

Optical coherence tomography: fundamentals and clinical utility

Subban

Raffel²

2020

Cardiovasc Diagn Ther

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Saline as an Alternative to Radio-Contrast for Optical Coherence Tomography-Guided Percutaneous Coronary Intervention: A Prospective Comparison

Gupta¹,

Chhikara

Vijayvergiya

et al. 2022

Cardiovascular Revascularization Medicine

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Investigations of injection strategies to use heparinized normal saline instead of contrast media for intracoronary optical coherence tomography imaging

Zebrauskaite,

Tsybulskyi,

Simanauskas

et al. 2024

Perfusion

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Background The benefits of intravascular imaging-guided percutaneous coronary interventions (PCI) are well established. Intravascular imaging guidance improves short- and long-term outcomes, especially in complex PCI. Optical coherence tomography (OCT) has a higher resolution than intravascular ultrasound. However, the usage of OCT is mainly limited by the need to use contrast for flushing injections, which increases the risk of contrast-induced acute kidney injury, especially in patients with underlying chronic kidney disease. The aim of this study was to prove that flushing techniques with normal saline instead of contrast can be used in OCT imaging and can generate high-quality images. Methods This prospective single-center observational study included patients with indications for OCT-guided PCI. For OCT pullbacks, heparinized saline was injected by an automatic pump injector at different rates, and additional extension catheters for selective coronary artery engagement were used at the operator’s discretion. Recordings were made using the Ilumien Optis OCT system (Abbott) and the Dragonfly (Abbott) catheter and were analyzed at 1-mm intervals by two operators. Pullbacks were categorized as having optimal, acceptable, or unacceptable imaging quality. A clinically usable run was determined if >75% of the region of interest length was described as having optimal or acceptable imaging quality. Results A total of 32 patients were enrolled in the study; 47 different lesions were assessed before and after PCI. In total, 91.5% of runs were described as clinically suitable for use. Conclusion Heparinized saline injections for OCT imaging are effective in generating good-quality OCT images suitable for clinical use.

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Zero contrast optical coherence tomography–guided percutaneous coronary intervention for in-stent restenosis of the saphenous vein graft using a non-contrast flush medium

Cited by 4 publications

References 9 publications

Optical coherence tomography: fundamentals and clinical utility

Optical coherence tomography: fundamentals and clinical utility

Saline as an Alternative to Radio-Contrast for Optical Coherence Tomography-Guided Percutaneous Coronary Intervention: A Prospective Comparison

Investigations of injection strategies to use heparinized normal saline instead of contrast media for intracoronary optical coherence tomography imaging

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