“…Therefore, much effort has been oriented toward the judicious design and synthesis of appropriate fluorescence sensors for the quantitative detection and determination of various metal ions. , Zn(II) ion is an essential element that influences various biological activities that play significant roles in environmental and biological systems. , Zinc is the second most abundant metal ion in the biological system. It is crucial for maintaining normal cellular activities, including cell division, mammalian reproduction, muscle contraction, hormone regulation, protein synthesis, and DNA synthesis. − In the human body, the normal Zn(II) level is between 200 and 300 mg, and deviation of zinc levels (above or below) from this value can cause many health problems. A deficiency of Zn(II) may cause several symptoms of diseases, such as brain dysfunction, Parkinson’s disease, immune suppression, skin damage, diabetes, and slow growth .…”