Zinc selective chemosensors based on the flexible dipicolylamine and quinoline

A hexa-quinoline basedC3-symmetric chemosensor for dual sensing of zinc(ii) and PPi in an aqueous mediumviachelation induced “OFF–ON–OFF” emission

“…Zinc is the second most abundant transition metal occurring in the human body and plays diverse roles in several vital biological processes like cellular metabolism, neurotransmission, etc. [1][2][3][4][5][6][7][8][9][10][11] In everyday life, zinc is found in various foods, automobiles, sunscreens, cosmetics and surgical tools etc. It exists mostly as Zn 2+ in the body as well as in nature.…”

“…12 However, misregulation of Zn 2+ causes several diseases like Alzheimer's, epilepsy, infantile diarrhea, prostate cancer, etc. [1][2][3][4][5][6][7][8][9][10][11][13][14][15][16][17] On the other hand, pyrophosphate (PPi), which is produced during ATP hydrolysis, is a crucial anion for normal cell functioning, e.g., it is involved in DNA polymerase catalyzed DNA replication and real time DNA sequencing. [18][19][20][21][22][23][24][25][26][27][28][29] So, it is highly desirable to explore efficient methods to detect and monitor Zn 2+ and PPi in environmental as well as in biological samples.…”

“…[1][2][3][4][5]12,[20][21][22][23][24][25][26] Here, it has to be mentioned that, due to the almost similar electronic properties of Cd 2+ and Zn 2+ , it is indeed difficult to develop a selective chemosensor for Zn 2+ without the interference of Cd 2+ . [30][31][32][33][34] Though an ample number of fluorescence sensors for Zn 2+ have been reported based on di-2-picolylamine (DPA), 9,10,[15][16][17][35][36][37][38][39][40] quinoline, 1,8,10,15,35,41-46 bipyridyl 1,47 etc.…”

Quinoline-functionalized norbornene for fluorescence recognition of metal ions

“…Among them, the carboxamidoquinoline derivatives have attracted much attention for their tunable bonding mode. According to the types of the auxiliary binding sites and the center metal ions (Scheme 1), the carboxamidoquinoline ligands can bind with metal ions in an amide tautomeric form (type I) [30][31][32], an imidic acid tautomeric form (type II) [33,34], and a deprotonation amide tautomeric form (type III) [35][36][37][38].…”

“…With tunable and suitable coordination structure, some sophisticated carboxamidoquinoline-base sensors for recognition of various metal ions, such as Zn 2+ , Cd 2+ and Cu 2+ , have been developed [30][31][32][33][34][35][36][37][38][39][40]. However, systems for recognition of Hg 2+ are still unknown, to the best of our knowledge.…”