Zinc‐Terpyridine Based Chemosensor for Detection of Pyrophosphate Anion in Aqueous Medium

Abstract

A simple fluorescent sensor of zinc-terpyridine complex of the terpyridine ligand 4'-(3,4,5-trimethoxyphenyl)-2,2' : 6',2''-terpyridine was prepared and utilized for selective sensing of pyrophosphate anion (PPi) in aqueous medium at physiological pH. The sensor complex showed an excellent selectivity of PPi over various other anions such as Cl À , F À , Br À , I À , CO 3 2À , HCO 3 À , NO 3 À , OH À , HPO 4 2À , SO 4 2À , SO 3 2À , S 2 O 3 2À in water. UV-Visible and fluorescence spectroscopic method have been used to perform the detection study. The sensor complex showed~50 fold enhancement of fluorescence intensity upon addition of PPi and excellent sensitivity with lowest limit of detection (LOD) for the detection of PPi anion was found to be~300 nM.

Selective pyrophosphate detection via metal complexes

“…Terpyridine was first reported in 2011, and its zinc complex was subsequently found to exhibit fluorescence turn‐on and partial selectivity for PPi, AMP, and ADP under various conditions [59]. Several groups reported similar terpyridine derivatives for PPi sensing [60–64]. Here, we analyzed these derivatives to further understand the unique sensing mechanism (Table 2, No.…”

Recent developments in the synthesis and applications of terpyridine-based metal complexes: a systematic review

“…The sensor showed a uorescence intensity of about ∼50 folds on the addition of PPi anions and the sensitivity detection limit was about ∼300 nm. 123 Rodrígueze et al (2021) elucidated the properties of uorescent zinc-based TPY complexes, exemplied by complex 322 (Fig. 25).…”

“…The sensor showed a fluorescence intensity of about ∼50 folds on the addition of PPi anions and the sensitivity detection limit was about ∼300 nm. 123 …”

A simple copper(ii) dppy-based receptor for sensing of l-cysteine and l-histidine in aqueous acetonitrile medium

“…Recently, nitrogenbased heterocyclic ligands such as 2,2′:6′,2″-terpyridine, 2,6-dipyrazinylpyridine (dppy), and their transition metal complexes have garnered significant attention due to their easy one-pot synthesis, high stability, fascinating electrochemical and photophysical properties, and potential physiological activities. [49][50][51][52][53] These ligands have been incorporated into various applications, including self-assembly, 54 hydrogelation, [55][56][57] halogen bonding, 58,59 and anion sensing, 60,61 etc.…”