ZrCl4 as a mild and efficient catalyst for the one-pot conversion of TBS and THP ethers to acetates

CAN/[nbp]FeCl4 as a reusable catalytic system for direct conversion of trimethylsilyl ethers to their acetates under microwave irradiation

“…On the other hand, no side products were observed by this method. Aliphatic trimethylsilyl ethers such as 1-heptyl-, cyclohexyl-or (-)-menthyl trimethylsilyl ethers also gave the corresponding acetates in high yields (Table 1, entries [16][17][18][19]. t-Butyl trimethylsilyl ether undergoes deprotection to generate only the corresponding alcohol, without producing any acetate.…”

“…Thus one-pot conversion of TMS ethers to the corresponding acetates could be considered as a useful transformation in organic synthesis. Nevertheless, the methods available for this transformation are limited [16,17]. Recently, we have reported that Bi(III) salts can catalyzed this transformation [18,19].…”

Hydrated ferric perchlorate, Fe(ClO4)3.XH2O in organic synthesis. A short review

“…The method available for the direct conversion of THP ethers to the corresponding acetates include FeCl 3 /Ac 2 O, AcOH/AcCl, Ti/Ac 2 O, bismuth salts, Cu(OTf) 2 /Ac 2 O and ZrCl 4 [63][64][65][66][67][68]. Ferric perchlorate in catalytic amounts can convert THP ethers directly and efficiently to the corresponding acetates in high yields in a one-pot reaction in the presence of acetic acid (Scheme 8) [69].…”

Some applications of zirconium(IV) tetrachloride (ZrCl4) and zirconium(IV) oxydichloride octahydrate (ZrOCl2.8H2O) as catalysts or reagents in organic synthesis

“…It was found that ZrCl 4 (5 mol%) and acetic anhydride reagent system has been used for selective conversion of ethers to the corresponding acetates under mild reaction conditions (Scheme 21) [46]. …”