β-Glucosidase: Structure, function and industrial applications

Thermal Sensitivity of the Enzymatic Activity of β-Glucosidase: Simulations Lend Mechanistic Insights into Experimental Observations

“…5 BG also plays a pivotal role in cellulose hydrolysis by preventing the inhibitory effects of cellobiose on EG and CBH, thus facilitating the complete breakdown of cellulose. 4 There are significant challenges in producing economically viable biofuel, partly due to the high cost of cellulase production and the inability of any microorganism to make the complete repertoire of necessary cellulolytic components in sufficient quantities. 3,5 To address the latter, optimal synergistic enzyme mixes or cocktails are typically designed from various microbial sources to hydrolyze pretreated biomass effectively.…”

“…BG completes the process by hydrolyzing the β-1,4 glycosidic linkage of cellobiose to generate glucose . BG also plays a pivotal role in cellulose hydrolysis by preventing the inhibitory effects of cellobiose on EG and CBH, thus facilitating the complete breakdown of cellulose …”