2024
DOI: 10.3390/molecules29040798
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β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

Chuntao Xu,
Jiawei Dai,
Hongxia Ai
et al.

Abstract: β-Nicotinamide mononucleotide (NMN) has shown promising effects on intestinal health, and it is extensively applied as an anti-aging and Alzheimer’s disease therapeutic, due to its medicinal properties. The effects of NMN on the growth of mouse hair were observed after hair removal. The results indicated that NMN can reverse the state of hair follicle atrophy, hair thinning, and hair sparsity induced by dihydrotestosterone (DHT), compared to that of minoxidil. In addition, the action mechanisms of NMN promotin… Show more

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“…The cells were then incubated in a CO 2 incubator at 37 °C with 5% CO 2 for 30 min. Subsequently, the culture medium containing DCFH-DA was removed, and the keratinocytes were washed three times with PBS, digested with trypsin (0.25%), and washed again with PBS before being subjected to flow cytometry cell analysis [ 53 ].…”
Section: Methodsmentioning
confidence: 99%
“…The cells were then incubated in a CO 2 incubator at 37 °C with 5% CO 2 for 30 min. Subsequently, the culture medium containing DCFH-DA was removed, and the keratinocytes were washed three times with PBS, digested with trypsin (0.25%), and washed again with PBS before being subjected to flow cytometry cell analysis [ 53 ].…”
Section: Methodsmentioning
confidence: 99%