Due to medical data privacy regulations, it is often infeasible to collect and share patient data in a centralised data lake. This poses challenges for training machine learning algorithms, such as deep convolutional networks, which often require large numbers of diverse training examples. Federated learning sidesteps this difficulty by bringing code to the patient data owners and only sharing intermediate model training updates among them. Although a high-accuracy model could be achieved by appropriately aggregating these model updates, the model shared could indirectly leak the local training examples.In this paper, we investigate the feasibility of applying differential-privacy techniques to protect the patient data in a federated learning setup. We implement and evaluate practical federated learning systems for brain tumour segmentation on the BraTS dataset. The experimental results show that there is a tradeoff between model performance and privacy protection costs.

T he scientific, academic, medical and data science communities have come together in the face of the COVID-19 pandemic crisis to rapidly assess novel paradigms in artificial intelligence (AI) that are rapid and secure, and potentially incentivize data sharing and model training and testing without the usual privacy and data ownership hurdles of conventional collaborations 1,2 . Healthcare providers, researchers and industry have pivoted their focus to address unmet and critical clinical needs created by the crisis, with remarkable results [3][4][5][6][7][8][9] . Clinical trial recruitment has been expedited and facilitated by national regulatory bodies and an international cooperative spirit 10-12 . The data analytics and AI disciplines have always fostered open

We demonstrate a method for generating a 3D virtual character performance from the audio signal by inferring the acoustic and semantic properties of the utterance. Through a prosodic analysis of the acoustic signal, we perform an analysis for stress and pitch, relate it to the spoken words and identify the agitation state. Our rule-based system performs a shallow analysis of the utterance text to determine its semantic, pragmatic and rhetorical content. Based on these analyses, the system generates facial expressions and behaviors including head movements, eye saccades, gestures, blinks and gazes. Our technique is able to synthesize the performance and generate novel gesture animations based on coarticulation with other closely scheduled animations. Because our method utilizes semantics in addition to prosody, we are able to generate virtual character performances that are more appropriate than methods that use only prosody. We perform a study that shows that our technique outperforms methods that use prosody alone.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, welldocumented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

Sponsored search represents a major source of revenue for web search engines. This popular advertising model brings a unique possibility for advertisers to target users' immediate intent communicated through a search query, usually by displaying their ads alongside organic search results for queries deemed relevant to their products or services. However, due to a large number of unique queries it is challenging for advertisers to identify all such relevant queries. For this reason search engines often provide a service of advanced matching, which automatically finds additional relevant queries for advertisers to bid on. We present a novel advanced matching approach based on the idea of semantic embeddings of queries and ads. The embeddings were learned using a large data set of user search sessions, consisting of search queries, clicked ads and search links, while utilizing contextual information such as dwell time and skipped ads. To address the large-scale nature of our problem, both in terms of data and vocabulary size, we propose a novel distributed algorithm for training of the embeddings. Finally, we present an approach for overcoming a cold-start problem associated with new ads and queries. We report results of editorial evaluation and online tests on actual search traffic. The results show that our approach significantly outperforms baselines in terms of relevance, coverage, and incremental revenue. Lastly, we opensource learned query embeddings to be used by researchers in computational advertising and related fields. KeywordsSponsored search; ad retrieval; word embeddings.