Cardiovascular and neurological manifestations associated with thiamine deficiency in Guinean prisons are common but not reported.We performed a prospective study of 38 cases related to vitamin B1 deficiency over a period of 4 years. In this population, the literature of traditional data gathered: frequency peak after thirty (92.6%) and clear representation male (sex ratio M/F: 18/1). The clinical symptomatology remains essentially dominated by sensorimotor polyneuropathy and pure sensory (52.2%), overall heart failure (31.5%) and to a lesser degree by Gayet Wernicke's encephalopathy (7.8%) and shoshin beriberi with severe evolution (5.2%). The study of nutritional status by body mass index (BMI) of the World Health Organization, by the criteria of Detsky and biological markers including albumin, shows that these patients are severely malnourished.

Introduction Tuberculosis of the central nervous system (CNS) remains endemic in developing countries with high morbidity and mortality despite advances in imaging and treatment. The objective of our work was to describe the diagnostic and therapeutic difficulties of this pathology in the context of a country with limited health resources. Materials and methods We retrospectively studied 8 cerebral tuberculosis abscess files, collected in the archives of the neurosurgery department of the Conakry University Hospital over a 5-year period (January 2013–December 2017). The diagnosis was made by scanning and by isolation of acid-fast bacilli (AFB) by direct examination of pus. Results Mean age was 33 years (9–56 years), sex, 5H 5 men/3F 3 women. History of pulmonary TB, 3 cases; TB contagious, 5 cases; TST ITR positive, 5 cases; associated visceral TB, 5 cases; HIV positive serology, 2 cases. The clinic was dominated by altered consciousness, 7 cases; focal signs, 7 cases; and fever, 5 cases. The site was hemispherical in 7 cases and one case in the posterior brain fossa. Treatment was medico-surgical in all patients. The evolution was favorable in 3 cases, the neurological sequelae in 3 cases, 2 cases of death, and 2 cases of recurrence. Conclusion Cerebral tuberculous abscesses constitute a medico-surgical emergency. Despite their rarity, morbidity and mortality remains high in the context of developing countries due to diagnostic and therapeutic delays.

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Cosmopolitan disease, hydatidosis is caused by the hydatid larvae of a tapeworm of Echinococcus granulosus canes developing in the liver, lungs, heart and central nervous system. The biological certainty of brain damage in West Africa is difficult to confirm because of the supposed rarity of this affection and the difficulties of accessibility to MRI and CT radiological data suggestive of the disease. We retrospectively analyzed the file of 268 patients hospitalized in the Neurology Department between 2010 and 2016 for the management of encephalic syndrome with cystic neuroradiological cerebral lesions. Biological and neuroradiological evidence of hydatidosis was reported in 12 patients (4, 47%). An encephalic and infectious syndrome: headache, nausea and vomiting, fever, disorders of consciousness, sensitivo-motor deficit with hemiparesis type, cerebellar syndrome and sometimes visual disorders, expression of intracranial hypertension was found in patients. These elements of intracranial hypertension objectified in most patients, were associated in 3 cases with liver disorders. The biological data haemagglutination, Eliza, moderate eosinophilia, radiological CT / MRI and the demonstration of scolex during percutaneous aspirations (2 cases) and on operative specimens were the diagnostic confirmation beam.

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