T o suppress the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for coronavirus disease 2019 (COVID-19), many countries have adopted social-isolation measures. 1,2 These efforts have been largely successful but have had major economic implications. As of June 2020, the Canadian federal fiscal response alone was an estimated $169.2 billion. 3 Further, unemployment in June 2020 was 12% 4 and real gross domestic product is projected to fall 8.4% in 2020. 5 These consequences have led to demands to reopen the economy quickly. 6,7 Reverse transcription polymerase chain reaction (RT-PCR) is primarily used to detect acute SARS-CoV-2. 8 Because of capacity constraints, RT-PCR testing was initially reserved for individuals presenting with symptoms consistent with COVID-19. 9-11 As capacity expanded and the initial wave of the epidemic was brought under control, however, testing was subsequently made available to people with minimal or no symptoms. 12 Modelling studies have estimated such individuals account for more than 50% of community transmission. 13-16 This is supported by studies that indicate viral shedding begins before symptom onset 17,18 and case series
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