We present PHANGS–ALMA, the first survey to map CO J = 2 → 1 line emission at ∼1″ ∼100 pc spatial resolution from a representative sample of 90 nearby (d ≲ 20 Mpc) galaxies that lie on or near the z = 0 “main sequence” of star-forming galaxies. CO line emission traces the bulk distribution of molecular gas, which is the cold, star-forming phase of the interstellar medium. At the resolution achieved by PHANGS–ALMA, each beam reaches the size of a typical individual giant molecular cloud, so that these data can be used to measure the demographics, life cycle, and physical state of molecular clouds across the population of galaxies where the majority of stars form at z = 0. This paper describes the scientific motivation and background for the survey, sample selection, global properties of the targets, Atacama Large Millimeter/submillimeter Array (ALMA) observations, and characteristics of the delivered data and derived data products. As the ALMA sample serves as the parent sample for parallel surveys with MUSE on the Very Large Telescope, the Hubble Space Telescope, AstroSat, the Very Large Array, and other facilities, we include a detailed discussion of the sample selection. We detail the estimation of galaxy mass, size, star formation rate, CO luminosity, and other properties, compare estimates using different systems and provide best-estimate integrated measurements for each target. We also report the design and execution of the ALMA observations, which combine a Cycle 5 Large Program, a series of smaller programs, and archival observations. Finally, we present the first 1″ resolution atlas of CO emission from nearby galaxies and describe the properties and contents of the first PHANGS–ALMA public data release.

We present the PHANGS-MUSE survey, a programme that uses the MUSE integral field spectrograph at the ESO VLT to map 19 massive (9.4 <  log(M⋆/M⊙)< 11.0) nearby (D ≲ 20 Mpc) star-forming disc galaxies. The survey consists of 168 MUSE pointings (1′ by 1′ each) and a total of nearly 15 × 106 spectra, covering ∼1.5 × 106 independent spectra. PHANGS-MUSE provides the first integral field spectrograph view of star formation across different local environments (including galaxy centres, bars, and spiral arms) in external galaxies at a median resolution of 50 pc, better than the mean inter-cloud distance in the ionised interstellar medium. This ‘cloud-scale’ resolution allows detailed demographics and characterisations of H II regions and other ionised nebulae. PHANGS-MUSE further delivers a unique view on the associated gas and stellar kinematics and provides constraints on the star-formation history. The PHANGS-MUSE survey is complemented by dedicated ALMA CO(2–1) and multi-band HST observations, therefore allowing us to probe the key stages of the star-formation process from molecular clouds to H II regions and star clusters. This paper describes the scientific motivation, sample selection, observational strategy, data reduction, and analysis process of the PHANGS-MUSE survey. We present our bespoke automated data-reduction framework, which is built on the reduction recipes provided by ESO but additionally allows for mosaicking and homogenisation of the point spread function. We further present a detailed quality assessment and a brief illustration of the potential scientific applications of the large set of PHANGS-MUSE data products generated by our data analysis framework. The data cubes and analysis data products described in this paper represent the basis for the first PHANGS-MUSE public data release and are available in the ESO archive and via the Canadian Astronomy Data Centre.

This study demonstrates a potency ratio of 81.2 (95% CI 73.0-89.7) for equivalence between phenylephrine and ephedrine in prevention of hypotension after spinal anaesthesia for Caesarean section.

We describe the processing of the PHANGS-ALMA survey and present the PHANGS-ALMA pipeline, a public software package that processes calibrated interferometric and total power data into science-ready data products. PHANGS-ALMA is a large, high-resolution survey of CO(2-1) emission from nearby galaxies. The observations combine ALMA's main 12 m array, the 7 m array, and total power observations, and use mosaics of dozens to hundreds of individual pointings. We describe the processing of the u − v data, imaging and deconvolution, linear

The PHANGS program is building the first data set to enable the multiphase, multiscale study of star formation across the nearby spiral galaxy population. This effort is enabled by large survey programs with the Atacama Large Millimeter/submillimeter Array (ALMA), MUSE on the Very Large Telescope, and the Hubble Space Telescope (HST), with which we have obtained CO(2–1) imaging, optical spectroscopic mapping, and high-resolution UV–optical imaging, respectively. Here, we present PHANGS-HST, which has obtained NUV–U–B–V–I imaging of the disks of 38 spiral galaxies at distances of 4–23 Mpc, and parallel V- and I-band imaging of their halos, to provide a census of tens of thousands of compact star clusters and multiscale stellar associations. The combination of HST, ALMA, and VLT/MUSE observations will yield an unprecedented joint catalog of the observed and physical properties of ∼100,000 star clusters, associations, H ii regions, and molecular clouds. With these basic units of star formation, PHANGS will systematically chart the evolutionary cycling between gas and stars across a diversity of galactic environments found in nearby galaxies. We discuss the design of the PHANGS-HST survey and provide an overview of the HST data processing pipeline and first results. We highlight new methods for selecting star cluster candidates, morphological classification of candidates with convolutional neural networks, and identification of stellar associations over a range of physical scales with a watershed algorithm. We describe the cross-observatory imaging, catalogs, and software products to be released. The PHANGS high-level science products will seed a broad range of investigations, in particular, the study of embedded stellar populations and dust with the James Webb Space Telescope, for which a PHANGS Cycle 1 Treasury program to obtain eight-band 2–21 μm imaging has been approved.