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Objectives: The aim of this study was to estimate the prevalence of depressive disorders and the influence of sociodemographic characteristics on primary healthcare (PHC) setting in Kuwait. Subjects and Methods: A cross-sectional survey was conducted in PHC setting in Kuwait using the Beck Depression Inventory second edition questionnaire (BDI II) as a screening instrument, together with a sociodemographic questionnaire. A representative sample drawn from the target population consisted of 2,320 subjects of Kuwaiti nationality randomly selected from 18 PHC centers covering all Kuwait governorates during the period from April 2003 to January 2004. The target age group was 21–64 years. Participants were asked to complete the BDI II questionnaire consisting of 21 items reflecting the depressive disorder independently. Sociodemographic data such as sex, age, marital status, children, occupation, educational status, chronic diseases and social problems were included in the questionnaire. The optimum cutoff score for BDI II was estimated. Results: A total of 2,320 participants completed the questionnaire, 1,082 (46.8%) male and 1,237 (53.2%) female; 860 (37.1%) screened positive for depressive symptoms, among whom 352 (15.3%) were male and 508 (21.7%) female. Of all participants, 163 (7.0%) were severely depressed, 314 (13.5%) moderately depressed and 383 (16.5%) mildly depressed. Depressive disorder was more prevalent among women than men, young than old, more among highly educated individuals, working participants, married individuals, and parents with 3 or more children. Conclusion: Depressive disorder is a highly prevalent condition among Kuwaiti patients attending PHC setting. Chronic diseases and social problems are risk factors for depressive disorder.

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BACKGROUNDThe incidence, risk factors, and outcome of stent thrombosis (ST) after percutaneous coronary intervention (PCI) in Middle Eastern patients are largely unknown.OBJECTIVETo determine the incidence, risk factors and outcome in our population.DESIGNRetrospective study of a prospective multicenter registry of consecutive patients who underwent PCI between January 2013 and February 2014 (JoPCR1).SETTING12 tertiary care centers in Amman and Irbid, Jordan.PATIENTS AND METHODSWe collected clinical baseline and follow-up data.MAIN OUTCOME MEASURESIncidence of stent thrombosis.RESULTSThe mean (standard deviation) age of patients (n=2426) was 59.0 (10.1) years and 20.6% were women. Stents (n=3038) were drug eluting (89.6%), bare metal (9.4%) or bioabsorbable (1.0%). After 1 year, 47 patients (1.97%) had ST, including 44 (94%) definite and 3 (6%) probable ST. Patients who had ST presented with sudden death (n=6; 12.2%) or with a nonfatal event (n=43; 87.8%). Nonfatal events included non-ST-segment elevation acute coronary syndrome (26; 53%), acute ST segment elevation myocardial infarction (n=15; 31%) or heart failure (n=2; 4.1%). ST was associated with significantly higher one-month (22.0% vs. 0.7%) and one-year (12.3% vs. 0.73%) mortality rates compared with patients who did not have ST (P<.001). ST patients were younger (mean age 52.9 years vs. 58.4 years), had heart failure (64% vs. 18%), left ventricular ejection fraction (LVEF) <45% (36% vs. 13%), ST-segment deviation (70% vs. 48%), and elevated cardiac biomarkers blood levels (62% vs. 40%). In the multivariate analysis, the only factor that was significantly associated with ST was the heart failure (OR = 3.5, 95% confidence interval: 1.8, 6.6; P<.0001).CONCLUSIONSThe incidence of ST was not different from that in other regions and was associated with an increased one-year mortality. Younger age, heart failure, low LVEF, ST-segment deviation, and elevated blood levels of cardiac biomarkers were predictors of ST.LIMITATIONSPossible selection bias, recall bias, and missing or incomplete information. The majority of patients were lost to follow up after the 6th month. The registry may not fully represent PCI practice and outcome in all areas in the country or region.

Aim:This is a prospective multicenter registry designed to evaluate the incidence of adverse cardiovascular events in Middle Eastern patients undergoing percutaneous coronary interventions (PCI). The registry was also designed to determine the predictors of poor outcomes in such patients.Methods and Results:We enrolled 2426 consecutive patients who underwent PCI at 12 tertiary care centers in Jordan between January 2013 and February 2014. A case report form was used to record data prospectively at hospital admission, discharge, and 12 months of follow-up. Mean age was 56 ± 11 years, females comprised 21% of the study patients, 62% had hypertension, 53% were diabetics, and 57% were cigarette smokers. Most patients (77%) underwent PCI for acute coronary syndrome. In-hospital and 1-year mortality rates were 0.78% and 1.94%, respectively. Definite or probable stent thrombosis occurred in 9 patients (0.37%) during hospitalization and in 47 (1.94%) at 1 year. Rates of target vessel repeat PCI and coronary artery bypass graft surgery at 1 year were 3.4% and 0.6%, respectively. The multivariate analysis revealed that cardiogenic shock, congestive heart failure, ST-segment deviation, diabetes, and major bleeding were significantly associated with higher risk of 1-year mortality.Conclusions:In this first large Jordanian registry of Middle Eastern patients undergoing PCI, patients treated were relatively young age population with low in-hospital and 1-year adverse cardiovascular events. Certain clinical features were associated with worse outcomes and may warrant aggressive therapeutic strategies.