5mm 5 mm Highlights Total cross-sectional SPSS area (TSA) predicts survival in patients with advanced chronic liver disease. The cutoff for TSA that is associated with worse survival corresponds to a single shunt of >10 mm diameter. This study may impact on the clinical use of TSA/SPSS for risk stratification and decision-making in the management of patients with cirrhosis.

Background Acute pancreatitis (AP) is a frequent disorder with considerable morbidity and mortality. Obesity has previously been reported to influence disease severity. Objective The aim of this study was to investigate the association of adipose and muscle parameters with the severity grade of AP. Methods In total 454 patients were recruited. The first contrast-enhanced computed tomography of each patient was reviewed for adipose and muscle tissue parameters at L3 level. Associations with disease severity were analysed through logistic regression analysis. The predictive capacity of the parameters was investigated using receiver operating characteristic (ROC) curves. Results No distinct variation was found between the AP severity groups in either adipose tissue parameters (visceral adipose tissue and subcutaneous adipose tissue) or visceral muscle ratio. However, muscle mass and mean muscle attenuation differed significantly with p-values of 0.037 and 0.003 respectively. In multivariate analysis, low muscle attenuation was associated with severe AP with an odds ratio of 4.09 (95% confidence intervals: 1.61–10.36, p-value 0.003). No body parameter presented sufficient predictive capability in ROC-curve analysis. Conclusions Our results demonstrate that a low muscle attenuation level is associated with an increased risk of severe AP. Future prospective studies will help identify the underlying mechanisms and characterise the influence of body composition parameters on AP.

In cystic abdominal masses in early childhood or young adults, abdominal LM must be taken into account by the radiologist. Newly defined entities in this spectrum of diseases are central conducting lymphatic anomaly (CCLA) and generalized lymphatic anomaly (GLA).

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Number of figures and tables: figures 2; tables 4, supplementary tables 3 Abbreviations: cHE-covert hepatic encephalopathy; CFF-critical flicker frequency; HE-hepatic encephalopathy; HR-hazard ratio; IQR-interquartile range; MRI-magnetic resonance imaging; OR-odds ratio; oHE-overt hepatic encephalopathy; PHES-psychometric hepatic encephalopathy score; SBP-spontaneous bacterial peritonitis; SPSS-spontaneous portosystemic shunt; TIPStransjugular intrahepatic portosystemic shunt, TSA-total SPSS area. Disclosures/Conflict of interest: none Ethical approval statement: Institutional review board approval for the present study was obtained. (Ethics committee University of Halle: 2016-36) Patient consent statement: N/A Trial registration number: N/A Funding statement (Grant Support): MST is a recipient of a Juan Rodés grant from Instituto de Salud Carlos III, Spain. JG is a recipient of a Research Intensification grant from the Instituto de Salud Carlos III. The work was partially funded by grant PI18/00947 from Instituto de Salud Carlos III and co-funded by European Union (ERDF/ESF, "Investing in your future"-Una manera de hacer Europa). CIBERehd is supported by Instituto de Salud Carlos III.