No abstract

We are very uncertain whether HPN improves survival or quality of life in people with MBO as the certainty of evidence was very low for both outcomes. As the evidence base is limited and at high risk of bias, further higher-quality prospective studies are required.

Synthesis of the longest heparin-related oligosaccharide backbones is enabled by efficient iterative [4]n-mer homologations via solution-phase synthesis. Pure-Shift HSQC NMR provides a dramatic improvement in anomeric signal resolution.