Long-term follow-up analysis suggested that both SMILE and FS-LASIK were safe and equally effective for myopic and astigmatic correction.

AimsTo predict the vault and the EVO-implantable collamer lens (ICL) size by artificial intelligence (AI) and big data analytics.MethodsSix thousand two hundred and ninety-seven eyes implanted with an ICL from 3536 patients were included. The vault values were measured by the anterior segment analyzer (Pentacam HR). Permutation importance and Impurity-based feature importance are used to investigate the importance between the vault and input parameters. Regression models and classification models are applied to predict the vault. The ICL size is set as the target of the prediction, and the vault and the other input features are set as the new inputs for the ICL size prediction. Data were collected from 2015 to 2020. Random Forest, Gradient Boosting and XGBoost were demonstrated satisfying accuracy and mean area under the curve (AUC) scores in vault predicting and ICL sizing.ResultsIn the prediction of the vault, the Random Forest has the best results in the regression model (R2=0.315), then follows the Gradient Boosting (R2=0.291) and XGBoost (R2=0.285). The maximum classification accuracy is 0.828 in Random Forest, and the mean AUC is 0.765. The Random Forest predicts the ICL size with an accuracy of 82.2% and the Gradient Boosting and XGBoost, which are also compatible with 81.5% and 81.8% accuracy, respectively.ConclusionsRandom Forest, Gradient Boosting and XGBoost models are applicable for vault predicting and ICL sizing. AI may assist ophthalmologists in improving ICL surgery safety, designing surgical strategies, and predicting clinical outcomes.

Purpose To investigate the correlation between corneal densitometry, corneal topographic parameters, and corneal biomechanical properties in keratoconus. Methods A total of 76 eyes of 76 keratoconus patients were enrolled in this cross-sectional study. Corneal densitometry and topography were measured using Pentacam HR. Corneal biomechanical properties were measured using CorVis ST. Results The corneal densitometry values of the anterior 0 to 2 and 2 to 6 mm layers significantly correlated with the maximum keratometry values ( R = 0.373, P = 0.001 and R = 0.276, P = 0.016, respectively), thinnest corneal thickness values ( R = −0.331, P = 0.003 and R = −0.234, P = 0.042, respectively), anterior corneal elevation ( R = 0.392, P < 0.001 and R = 0.323, P = 0.004, respectively), and posterior corneal elevation ( R = 0.450, P < 0.001 and R = 0.367, P = 0.001, respectively). The stiffness parameter-applanation time 1 (SP-A1) significantly correlated with the corneal densitometry values for the anterior 0 to 2 mm ( R = −0.397, P < 0.001), anterior 2 to 6 mm ( R = −0.331, P = 0.004), central 0 to 2 mm ( R = −0.306, P = 0.007), central 2 to 6 mm ( R = −0.228, P = 0.048), posterior 2 to 6 mm ( R = −0.243, P = 0.035), total 0 to 2 mm ( R = −0.291, P = 0.011), and total 2 to 6 mm ( R = −0.295, P = 0.010) layers. Conclusions The corneal densitometry values correlated with the severity of keratoconus and the SP-A1 values. Translational Relevance Corneal densitometry values may serve as markers to predict the severity of keratoconus.