BackgroundWith the recent widespread use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), there have been occasional reports on complications associated with its use. Previous reviews on EBUS-TBNA have been limited to studies by skilled operators, thus the results may not always be applicable to recent clinical practice. To assess the safety of EBUS-TBNA for the staging and diagnosis of lung cancer in Japan, a nationwide survey on its current usage status and complications associated with its use was conducted by the Japan Society for Respiratory Endoscopy (JSRE).MethodsA questionnaire about EBUS-TBNA performed between January 2011 and June 2012 was mailed to 520 JSRE-accredited facilities.ResultsResponses were obtained from 455 facilities (87.5%). During the study period, EBUS-TBNA was performed in 7,345 cases in 210 facilities (46.2%) using a convex probe ultrasound bronchoscope, for 6,836 mediastinal and hilar lesions and 275 lung parenchymal lesions. Ninety complications occurred in 32 facilities. The complication rate was 1.23% (95% confidence interval, 0.97%-1.48%), with hemorrhage being the most frequent complication (50 cases, 0.68%). Infectious complications developed in 14 cases (0.19%) (Mediastinitis, 7; pneumonia, 4; pericarditis, 1; cyst infection, 1; and sepsis, 1). Pneumothorax developed in 2 cases (0.03%), one of which required tube drainage. Regarding the outcome of the cases with complications, prolonged hospitalization was observed in 14 cases, life-threatening conditions in 4, and death in 1 (severe cerebral infarction) (mortality rate, 0.01%). Breakage of the ultrasound bronchoscope occurred in 98 cases (1.33%) in 67 facilities (31.9%), and that of the puncture needle in 15 cases (0.20%) in 8 facilities (3.8%).ConclusionsAlthough the complication rate associated with EBUS-TBNA was found to be low, severe complications, including infectious complications, were observed, and the incidence of device breakage was high. Since the use of EBUS-TBNA is rapidly expanding in Japan, an educational program for its safe performance should be immediately established.

The long-term outcome (> 10 years) after cervical laminoplasty was assessed and the postoperative problems were clarified. One hundred thirty-three patients had laminoplasty between 1981 and 1989 for treatment of cervical myelopathy and 126 patients were available for the current study. The clinical results were evaluated using the Japanese Orthopaedic Association score. The radiologic findings were analyzed by postural anomalies and range of motion. The average preoperative score was 9.1 points, and the postoperative score improved to 13.7 points within a year. The Japanese Orthopaedic Association score and recovery rate were maintained at 13.4 points and 55.1% at the last followup. In 20 patients, the Japanese Orthopaedic Association score worsened during the followup. The causes of deterioration were axial spread of ossification of the posterior longitudinal ligament, other spinal lesions, cerebral infarction, and peripheral neuropathy. Postoperative cervical radiculopathy occurred in nine patients. Postoperative radiculopathy resolved in five patients, but remained in four patients. Kyphotic changes were observed in eight patients. The recovery rate in patients with kyphosis was poor. The postoperative range of motion decreased to 25.1% of preoperative range of motion. Sixty one percent of patients had a reduction of range of motion. Satisfactory results of cervical laminoplasty were maintained for more than 10 years after surgery; however, there were several postoperative problems, such as neurologic deterioration, postoperative radiculopathy, progression of kyphosis, and range of motion limitation.

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