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The results of our prospective study have revealed great diversity in the treatment regimens used to manage MM in real-life practice. This diversity was linked to factors such as novel agent accessibility and evolving treatment recommendations. Our results provide insight into associated clinical benefits.

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ReuseItems deposited in White Rose Research Online are protected by copyright, with all rights reserved unless indicated otherwise. They may be downloaded and/or printed for private study, or other acts as permitted by national copyright laws. The publisher or other rights holders may allow further reproduction and re-use of the full text version. This is indicated by the licence information on the White Rose Research Online record for the item. TakedownIf you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing eprints@whiterose.ac.uk including the URL of the record and the reason for the withdrawal request.PHYSICAL REVIEW C 94, 025205 (2016) Determination of the real part of the η ′ -Nb optical potential The excitation function and momentum distribution of η ′ mesons have been measured in photoproduction off 93 Nb in the energy range of 1.2-2.9 GeV. The experiment has been performed with the combined Crystal Barrel and MiniTAPS detector system, using tagged photon beams from the ELSA electron accelerator. Information on the sign and magnitude of the real part of the η ′ -Nb potential has been extracted from a comparison of the data with model calculations. An attractive potential of −(41 ± 10(stat) ± 15(syst)) MeV depth at normal nuclear matter density is deduced within model uncertainties. This value is consistent with the potential depth of −(37 ± 10(stat) ± 10(syst)) MeV obtained in an earlier measurement for a light nucleus (carbon). This relatively shallow η ′ -nucleus potential will make the search for η ′ -nucleus bound states more difficult.

In a search for ω mesic states, the production of ω-mesons in coincidence with forward going protons has been studied in photon induced reactions on 12 C for incident photon energies of 1250 -3100 MeV. The π 0 γ pairs from decays of bound or quasi-free ω-mesons have been measured with the CBELSA/TAPS detector system in coincidence with protons registered in the MiniTAPS forward array. Structures in the total energy distribution of the π 0 γ pairs, which would indicate the population and decay of bound ω 11 B states, are not observed. The π 0 γ cross section of 0.3 nb/MeV/sr observed in the bound state energy regime between -100 and 0 MeV may be accounted for by yield leaking into the bound state regime because of the large in-medium width of the ωmeson. A comparison of the measured total energy distribution with calculations suggests the real part V 0 of the ω 11 B potential to be small and only weakly attractive with V 0 (ρ = ρ 0 ) = −15± 35(stat) ±20(syst) MeV in contrast to some theoretical predictions of attractive potentials with a depth of 100 -150 MeV.