Meningiomas are rare intracranial neoplasms in childhood and adolescence, representing 0.4–4.1% of the pediatric-age tumors and 1.5–1.8% of all intracranial meningiomas. The goal of this study was to determine epidemiology, clinical and radiological features, and long-term outcome of childhood and adolescence meningiomas. Patients operated for intracranial meningiomas of childhood and adolescence between 1983 and 2003 at Gazi University School of Medicine, Department of Neurosurgery, were evaluated retrospectively. This study presents 11 cases (6 male, 5 female), ranging in age from 14 months to 17 years. Age and sex distribution, presenting symptoms, neurological examination results, location of meningiomas, radiological and histopathological findings, and prognosis were reviewed. The results were compared with those reported in the existing literature. Atypical and malignant meningiomas seem to be more common in childhood and adolescence with respect to adult meningiomas. Tumor location, completeness of tumor removal, and pathological grade are the most important prognostic factors.

This article aims to describe an extraordinary complication of a ventriculoperitoneal shunt system that formed a knot spontaneously and lead to a shunt malfunction. A 3-year-old male patient was operated due to posttraumatic hydrocephalus. After an uneventful follow-up period of 34 months, he presented with shunt malfunction. During the shunt revision surgery, the peritoneal catheter was found to form a loop over itself. There are various complications of ventriculoperitoneal shunt systems. Migration to body cavities is among the most interesting ones. This is the fifth report describing this rare complication. Hydrocephalic patients should be closely followed up after shunt surgery for various extraordinary complications. KeywOrds: V/P Shunt, Shunt Complication, Shunt Malfunction ÖZBu makale, kendi üzerine katlanarak bir düğüm oluşturup şant malfonksiyonuna neden olan ventriküloperitoneal şant sisteminin yol açtığı bu sıradışı bir komplikasyonu incelemektedir. Travma sonrasında gelişen hidrosefali nedeni ile opere edilen 3 yaşındaki erkek hasta 34 aylık sorunsuz bir takip süresi ardından şant malfonksiyonu ile başvurdu. Şant revizyonu sırasında peritoneal kateterin kendi üzerine katlanarak bir düğüm oluşturduğu gözlendi. Ventriküloperitoneal şant sistemlerine ait birçok farklı komplikasyon bildirilmiştir. Vücut boşluklarına migrasyon bu komplikasyonlardan en ilginç olanlar arasındadır. Bu makalede, sunulan vaka literatürdeki beşinci vakadır. Hidrosefalili hastalar şant cerrahisi sonrasında bu komplikasyonlar için yakın takipte tutulmalıdırlar.

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Although further studies considering different dose regimens and time intervals are required, the results of the present study prove that alpha-lipoic acid has favorable effects on experimental spinal cord ischemia-reperfusion injury.

Cytokines play a critical role in wound healing, tissue repair, and fibrogenesis. This study suggests that topical application of low-dose IFN-gamma is an effective and safe method of preventing peridural fibrosis, but further studies with different doses, durations, and intervals are required to achieve better results.