The clinical spectrum of dengue fever ranges from asymptomatic infection to dengue shock syndrome. Dengue is classically considered a non-neurotropic virus. Neurological complications are not commonly seen in dengue. The neurological manifestations seen in dengue are encephalitis, meningitis, encephalopathy, stroke and Guillain-Barré syndrome. Dengue encephalitis is a rare disease. We report an interesting case of dengue encephalitis from Southern India. A 49-year-old gentleman presented with fever, altered sensorium and seizures. Dengue NS-1 antigen test was reactive. Dengue IgM was also positive. CSF PCR was negative for herpes simplex 1 & 2. Dengue encephalitis should be considered in the differential diagnosis of fever with altered sensorium, especially in countries like India where dengue is rampant.

The classical presentation of typhoid has changed over the years. Atypical presentation of typhoid is now seen in clinical practice. Entericfever can present with atypical manifestations like abdominal lymphadenopathy, acute acalculous cholecystitis, osteomyelitis, splenic abscess and Pneumonia. Jaundice splenic abscess and thrombocytopenia in a febrile patient in the tropics is commonly due to Malaria, Leptospirosis and Dengue. We report a case of typhoid fever presenting with jaundice and thrombocytopenia. A 17 year old male presented to us with history of fever and jaundice. Investigations revealed thrombocytopenia and conjugated hyperbilirubinemia. Blood culture grew Salmonella Typhi. He was treated with ceftriaxone and he improved. A diagnosis of typhoid fever must be considered in a febrile patient with jaundice and thrombocytopenia in the tropics.

Background: Rabies is the only communicable disease of man that is 100 percentage fatal, yet it is easily preventable with timely and appropriate administration of vaccine and immunoglobulin. Rabies is still a neglected disease and the study was undertaken to determine the socio-demographic, clinical profile and the immunisation status of patients admitted with rabies in Epidemic Disease hospital, Mysore.Methods: The study was done retrospectively by observation of case records and registers for a period of ten years from 2008 to 2017.Results: Case records of 44 patients admitted with rabies were obtained. Most of them were males above the age of 40 years and reported history of dog bite (72.7%). Majority had symptoms 1-2 months after the animal bite. The classical symptoms of hydrophobia were present in 86.4% patients. All the 44 patients expired in the hospital. None of them had a complete post exposure prophylaxis of antirabies vaccination and immunoglobulin. The reasons for the same were obtained from case records and by interviewing the doctor in charge. The non-availability of vaccine and immunoglobulin, decreased knowledge and expertise in administration of immunoglobulin among hospital staff in the periphery were some of the reasons.Conclusions: The cost incurred, loss of wages and not understanding the importance of completion of anti-rabies vaccination by the animal bite victims can be addressed only by providing the immunoglobulin and vaccine at very low costs, adequate training of doctors and ensuring the availability of vaccine and drugs.