In this study, we compared the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) performance of male university students and incarcerated criminal offenders in Mexico. Our aim was to determine whether the MMPI-2 can effectively differentiate between these two distinct groups on scales that are reflective of antisocial behaviors. Our expectations were highly confirmed across the three sets of scales that we considered: the validity and clinical, content, and supplementary scales. Criminal offenders obtained higher or more pathological scores on such scales as Infrequency (F), Schizophrenia (Sc), MacAndrew Alcoholism Scale (MAC-R), Fears (FRS), and so on. Overall, these findings support further research with such target populations as prison inmates in Mexico and other countries in Latin America.
Background
Depressive symptoms, such as depressed mood, are common in older adults and associated with an increased risk for morbidity and mortality. Given the evidence that sleep disturbance and alterations in interferon (IFN)-γ biology are associated with depression risk, this study examines the separate and joint contributions of poor sleep maintenance and IFN-γ to depressed mood in older adults.
Methods
Community-dwelling, non-depressed older adults (n = 36, 72.1 ± 6.8 years) underwent a night of polysomnography to assess sleep maintenance [i.e. wake time after sleep onset (WASO)]. The morning after polysomnography, plasma levels of IFN-γ were evaluated along with self-reported depressed mood throughout the day. Multivariate linear regression tested associations of WASO and IFN-γ with the severity of depressed mood. In addition, moderation and mediation models examined the role of IFN-γ for the relationship between WASO and depressed mood.
Results
A greater amount of WASO (p < 0.05) and higher levels of IFN-γ (p < 0.01) were both associated with the severity of depressed mood. Moreover, IFN-γ moderated the relationship between WASO and depressed mood (p < 0.01), such that WASO was more strongly related to the depressed mood among those with higher IFN-γ, than among those with lower IFN-γ. However, IFN-γ did not mediate the relationship between WASO and depressed mood.
Conclusion
In this study of older adults, poor sleep maintenance and higher levels of IFN-γ were both related to depressed mood. Moreover, IFN-γ moderated the relationship between poor sleep maintenance and depressed mood. Together, these findings suggest that older adults with higher IFN-γ are at heightened risk for depressive symptoms following sleep disturbance.
Performance of 82 Colombian, 87 Mexican, and 96 Venezuelan university students and adult community dwellers on Spanish translations of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) were compared. Findings suggest more comprehensive research is required on applications of the MMPI-2 in Latin America and greater consideration of the roles of culture and nationality.
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