Holocord spinal abscesses are a rare entity. The source of the disease can be hemopoietic spread or contagious spread. The dermal sinus tract is major risk factor for contagious spread. The major hemopoietic sources are urogenital infection, endocarditis, and infective lung diseases. The hemopoietic spread is a more common source for pediatric patients. The thoracolumbar region is the most common site of involvement. Spinal infection has a tendency to extend longitudinally throughout spinal fibers. The pathogenesis of the holocord edema or syrinx is uncertain. The underlying etiology may be inflammation, infection, and associated venous congestion within the spinal canal. Also, CSF circulation alteration due to arachnoiditis may be another etiological factor. The most important entities on outcome are appropriate surgical treatment and antibiotic administration.

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Sleep deprivation, which is a type of sleep disorder, generates oxidative stress in an organism and has acute and chronic adverse effects on well-being by causing biochemical changes. Although the acute manifestations mainly include disturbed neuromediator homeostasis in the central nervous system, changes in hormonal regulation and alterations in sympathetic and parasympathetic system activity, eating disorders, psychosocial disorders, thermoregulation disorders and a disturbed blood lipid profile occur in the chronic period and can result in morbidity and mortality (Pilcher & Huffcutt 1999). Disorders of connective tissue elements and impairments in the regulation of connective tissue mediators associated with sleep deprivation may lead to prolonged wound healing and deterioration of immunity, and induce negative regulation systems in ageing physiology (Opp & Toth 2003).