Objective: This study evaluated the feasibility, acceptability, and preliminary efficacy of psychoeducation plus an automated text-messaging intervention (iTAB-CV) to improve adherence for antihypertensives and bipolar disorder medication. Methods: Following a psychoeducation program, iTAB-CV was administered for two months. In month one, participants received one educational/motivational and one mood rating text daily. In month two, medication reminders were added. Results: The sample (n=38) was 74% African-Americans, 53% women, with a mean age of 51.53±9.06. Antihypertensive non-adherence decreased from 43%±23% to 21%±26% at 12 weeks [χ 2 = 34.6, df= 3, p< 0.001]. SBP decreased from 144.8±15.5 mmHg to 136.0±17.8 mmHg (χ 2 = 17.6, df=3, p< 0.001). Retention was 100%. Conclusions: In this uncontrolled trial, participants were highly engaged and medication adherence and reduced SBP were sustained following psychoeducation plus iTAB-CV. Since iTAB-CV is automated and delivered remotely, it has potential to reach a large and challenging population.
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