BackgroundThe impact of blood pressure (BP) during adolescence on other cardiovascular risk
factors in young adults is important for the primary prevention. ObjectiveTo evaluate BP, anthropometric indexes, metabolic and inflammatory profiles in
young individuals stratified by their BP behavior recorded for 18 years. MethodsA total of 116 individuals, of whom 63 were males, from the Rio de Janeiro study
(follow-up of 17.76 ± 1.63 years), were assessed at two moments: A1 (12.40 ± 1.49
years) and A2 (30.09 ± 2.01 years). The 116 individuals were divided into two
groups: GN (n = 71), of participants with normal BP at A1; and GH (n = 45), of
those with abnormal BP at A1. BP, weight, height and body mass index (BMI) were
measured at A1 and A2. At A2, abdominal circumference (AC) and laboratory,
metabolic and inflammatory variables were included. Results1) No difference was observed between the groups as regards age and gender; 2) At
A2, GH showed higher mean weight, BMI, BP, insulin, HOMA-IR (p < 0.001), leptin
(p < 0.02), apolipoprotein B100 and A1 (p < 0.02), apolipoprotein B100 /
apolipoprotein A1 ratio (p < 0.010); and higher prevalences of
overweight/obesity (p < 0.001), of increased AC (p < 0.001) and of
hypertension (p < 0.02); 3) No difference was observed between the groups as
regards the inflammatory variables; 4) There was a positive correlation of BP at
A1 with BP, BMI, insulin, leptin and HOMA-IR at A2 (p < 0.05). ConclusionBP in adolescence was associated with higher values of BP, and anthropometric and
metabolic variables in young adulthood, but not with inflammatory variables.
