We report the flow behavior of water in microfluidic systems based on a chemically patterned anisotropic wetting surface. When water flows inside a microchannel on top of a micropatterned surface with alternating hydrophilic/hydrophobic stripes, it exhibits an anisotropic flowing characteristic owing to the anisotropic wettability; thus, the patterned surface acts as a microvalve for the microfluidic system. The anisotropic flow of water is influenced by the microscale features of the patterns and the dimensions of the microchannels. Furthermore, by reasonably combining the patterned surface and microchannel together, we realize the transportation of water in a microchannel along a "virtual" wall, which is the boundary of the hydrophilic and hydrophobic area. We believe that the chemically patterned surfaces could be an alternative strategy to control the flow behavior of water in microfluidic channels.

This article shows morphology-patterned stripes as a new platform for directing flow guidance of the fluid in microfluidic devices. Anisotropic (even unidirectional) spreading behavior due to anisotropic wetting of the underlying surface is observed after integrating morphology-patterned stripes with a Y-shaped microchannel. The anisotropic wetting flow of the fluid is influenced by the applied pressure, dimensions of the patterns, including the period and depth of the structure, and size of the channels. Fluids with different surface tensions show different flowing anisotropy in our microdevice. Moreover, the morphology-patterned surfaces could be used as a microvalve, and gas-water separation in the microchannel was realized using the unidirectional flow of water. Therefore, benefiting from their good performance and simple fabrication process, morphology-patterned surfaces are good candidates to be applied in controlling the fluid behavior in microfluidics.

In this paper, we demonstrate a facile strategy for the fabrication of a one-way valve for microfluidic (MF) systems. The micro-valve was fabricated by embedding arrays of Janus Si elliptical pillars (Si-EPAs) with anisotropic wettability into a MF channel fabricated in poly(dimethylsiloxane) (PDMS). Two sides of the Janus pillar are functionalized with molecules with distinct surface energies. The ability of the Janus pillar array to act as a valve was proved by investigating the flow behaviour of water in a T-shaped microchannel at different flow rates and pressures. In addition, the one-way valve was used to achieve gas-liquid separation. We believe that the Janus Si-EPAs modified by specific surface functionalization provide a new strategy to control the flow and motion of fluids in MF channels.

In this paper, Janus micropillar array (MPA) with fore-aft controllable wettability difference was demonstrated. With two-step modification process, we successfully decorate the Janus pillar skeletons with wettability-switchable polymer brush on one side and hydrophilic self-assembled monolayer on the other. Owing to the switchable wettability of the polymer brush, the patterned surface could switch between anisotropic wetting and isotropic wetting at different temperatures, which gives the possibility of coupling the well-designed surface with microfluidic channel to manipulate the microfluid motion. Additionally, a further photothermal control of microfluid was also established based on the thermal-responsive Janus MPA through introducing infrared light to adjust the temperature of the microfluidic system. We believe that the thermal-responsive Janus micropillar arrays would provide a new strategy to control the flow and motion of fluids in microfluidic channels and show potential applications in the future microfluidic chips.