BackgroundPigmented purpuric dermatosis is a chronic skin disorder of unknown aetiology
characterised by symmetrical petechial and pigmented macules, often confined
to the lower limbs. The aetiology of pigmented purpuric dermatosis is
unknown. Dermatoscopy is a non-invasive diagnostic technique that allows the
visualisation of morphological features invisible to the naked eye; it
combines a method that renders the corneal layer of the skin translucent
with an optical system that magnifies the image projected onto the
retina.ObjectivesThe aim of this study is to investigate the dermatoscopic findings of
pigmented purpuric dermatosis.MethodsThis study enrolled patients diagnosed histopathologically with pigmented
purpuric dermatosis who had dermatoscopic records. We reviewed the
dermatoscopic images of PPD patients who attended the outpatient clinic in
the Istanbul Dermatovenereology Department at the Bezmialem Vakıf University
Medical Faculty.ResultsDermatoscopy showed: coppery-red pigmentation (97%, n = 31) in the
background, a brown network (34%, n = 11), linear vessels (22%, n = 7),
round to oval red dots, globules, and patches (69%, n = 22; 75%, n = 24;
34%, n = 11; respectively), brown globules (26%, n = 8) and dots (53%, n =
17), linear brown lines (22%, n = 7), and follicular openings (13%, n =
4).ConclusionTo our knowledge, this is the first study to report the dermatoscopy of
pigmented purpuric dermatosis. In our opinion, dermatoscopy can be useful in
the diagnosis of pigmented purpuric dermatosis.
SummaryGiant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon. Visceral organ involvement including urinary bladder is rare. Giant cell tumors in visceral organs usually accompany epithelial tumors and the clinical behavior of giant cell tumor in urinary bladder is similar to its bone counterpart. Here, we report two cases of giant cell tumor located in urinary bladder in comparison with nine reported cases in the English literature. Concurrent noninvasive urothelial carcinoma was also described in all these previous reports and only one patient with follow-up died of disease. One of the two cases we present had no concurrent urothelial tumor at the time of diagnosis but had a history of a low grade noninvasive urothelial carcinoma with three recurrences. The histology of these two cases was similar to the giant cell tumor of bone and composed of oval to spindle mononuclear cells with evenly spaced osteoclast-like giant cells. Immunohistochemically, the giant cells showed staining with osteoclastic markers including CD68, TRAP, and LCA. Immunohistochemical expression of vimentin, CD68, LCA, and smooth muscle actin in mononuclear cells supported a mesenchymal origin with histiocytic lineage. The histologic and immunohistochemical properties in our cases as well as their clinical courses were consistent with a giant cell tumor. Consequently, tumors in urinary bladder showing features of giant cell tumor of bone may also be considered and termed "giant cell tumor".
maternity care services in Turkey need to recognise the potential impact of birth experiences on women's mental health and adaptation after birth. The importance of self-efficacy in pregnancy suggests antenatal education or support may protect women against developing post partum PTS, but this needs to be examined further.
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