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N6-methyladenosine (m6A) is a key area in Epigenetics and has been increasingly focused these years. In the m6A process, readers recognize the m6A modification on mRNAs or noncoding RNAs and mediate different downstream events. Emerging studies have shown that YTHDC1, an important m6A reader, plays a key role in many biological functions and disease progression, especially cancers. Here we summarized the current mechanisms of YTHDC1 in biological functions and diseases and offered guidance for future researches to provide potential strategy for clinical diagnose and therapy.

Pelvic schwannomas are rare and difficult to diagnose preoperatively. The intraoperative observation of the nerve running through the tumor may aid the diagnosis. Although obturator nerve injury does not seem to be associated with severe impairments, efforts should be made to preserve the integrity of the nerve. Laparoscopic surgery is a safe and feasible method for approaching benign schwannoma in the obturator fossa.