a b s t r a c tObjective: To evaluate the cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine (PCV10) versus the 13-valent PCV (PCV13) to the National Immunization Schedule in Peru for prevention of pneumococcal disease (PD) in children <5 years of age. Methods: The integrated TRIVAC vaccine cost-effectiveness model from the Pan American Health Organization's ProVac Initiative (version 2.0) was applied from the perspective of the Government of Peru. Twenty successive cohorts of children from birth to 5 years were evaluated. Clinical outcomes were pneumococcal pneumonia (PP), pneumococcal meningitis (PM), pneumococcal sepsis (PS) and acute otitis media from any causes (AOM). Measures included prevention of cases, neurological sequelae (NS), auditory sequelae (AS), deaths and disability adjusted life years (DALYs). A sensitivity analyses was also performed. Findings: For the 20 cohorts, net costs with PCV10 and PCV13 were US$ 363.26 million and US$ 408.26 million, respectively. PCV10 prevented 570,273 AOM; 79,937 PP; 2217 PM; 3049 PS; 282 NS; 173 AS; and 7512 deaths. PCV13 prevented 419,815 AOM; 112,331 PN; 3116 PM; 4285 PS; 404 NS; 248 AS;and 10,386 deaths. Avoided DALYs were 226,370 with PCV10 and 313,119 with PCV13. Saved treatment costs were US$ 37.39 million with PCV10 and US$ 47.22 million with PCV13. Costs per DALY averted were US$ 1605 for PCV10, and US$ 1304 for PCV13. Sensitivity analyses showed similar results. PCV13 has an extended dominance over PCV10. Conclusion: Both pneumococcal vaccines are cost effective in the Peruvian context. Although the net cost of vaccination with PCV10 is lower, PCV13 prevented more deaths, pneumococcal complications and sequelae. Costs per each prevented DALY were lower with PCV13. Thus, PCV13 would be the preferred policy; PCV10 would also be reasonable (and cost-saving relative to the status quo) if for some reason 13-valent were not feasible.

ObjectiveTo determine the prevalence of workplace violence among Peruvian medical residents and to evaluate the association between medical specialty and workplace violence per type of aggressor.MethodsThis was a cross-sectional secondary analysis that used data from the Peruvian Medical Residents National Survey 2016 (ENMERE-2016). The outcome of interest was workplace violence, including physical and verbal violence, which were categorized according to the perpetrator of violence (patients/relatives and worker-to-worker). Primary exposure was the medical specialty, categorized as clinical, surgical, and other specialties. To evaluate the associations of interest, we estimated adjusted prevalence ratios (PR) with their respective 95% confidence intervals (95% CI) using Poisson regression models with robust variances.ResultsA total of 1054 Peruvian medical residents were evaluated. The mean age was 32.6 years and 42.3% were female. Overall 73.4% reported having suffered of workplace violence sometime during the residency, 34.4% reported violence from patients/relatives, and 61.1% reported worker-to-worker violence. Compared with clinical residents, surgical residents had a lower prevalence of violence from patients/relatives (PR: 0.71; 95% CI: 0.59–0.87), but a higher prevalence of worker-to-worker violence (PR: 1.11, 95% CI: 1.01–1.23).ConclusionNearly three quarters of medical residents reported having suffered workplace violence sometime during their residency. Compared with clinical residents, surgical residents had lower rates of violence from patients/relatives, but higher rates of worker-to-worker violence; while residents from non-clinical and non-surgical specialties had a lower prevalence of both types of violence.

Aim. To determine the prevalence and the factors associated with the publication of scientifi c articles in medical residents of Peru. Subjects and methods. Cross-sectional analytical study using the data obtained by the National Survey for Resident Physicians 2016 (ENMERE-2016), carried out virtually during June 2016. Population: physicians who live in a university in Peru. Sample: residents who voluntarily participated in ENMERE-2016. Outcome of interest: have published at least one scientifi c article. Sociodemographic variables were collected, from the university, from the headquarters, from the residence, from the resident's perception, and from depressive symptoms. To evaluate the factors associated with having published a scientifi c article, crude and adjusted prevalence ratios were calculated with their 95% confi dence intervals. Results. Data from 1062 residents (42.2% female) were analyzed, of which 118 (11.1%) published some scientifi c paper during the resident. In the adjusted analysis, to study the superior years of residency, to have performed some external rotation outside the country and to have a higher score in the overall opinion of the training process were variables directly associated with having published some scientifi c article. While the female sex, being over 35 years old and presenting with depressive symptoms were variables inversely associated with this outcome. Conclusion. Approximately one in ten residents published a scientifi c article during the residency. This was less prevalent in women, in older residents, in those who were in lower years of residence, in those who did not perform any rotation outside the country, in those who had a worse opinion of the training process, and in those with depressive symptoms.

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