Abstract:We report on design, manufacture, and testing of a Slewing Mirror Telescope (SMT), the first of its kind and a part of Ultra-Fast Flash Observatory-pathfinder (UFFO-p) for space-based prompt measurement of early UV/optical light curves from Gamma-Ray Bursts (GRBs). Using a fast slewing mirror of 150 mm diameter mounted on a 2 axis gimbal stage, SMT can deliver the images of GRB optical counterparts to the intensified CCD detector within 1.5~1.8 s over ± 35 degrees in the slewing field of view. Its Ritchey-Chrétien telescope of 100 mm diameter provides a 17 × 17 arcmin 2 instantaneous field of view. Technical details of design, construction, the laboratory performance tests in space environments for this unique SMT are described in conjunction with the plan for in-orbit operation onboard the Lomonosov satellite in 2013.

We report on a measurement of the cosmic ray composition by the Telescope Array Low-Energy Extension (TALE) air fluorescence detector (FD). By making use of the Cherenkov light signal in addition to air fluorescence light from cosmic ray (CR) induced extensive air showers, the TALE FD can measure the properties of the cosmic rays with energies as low as ∼ 2 PeV and exceeding 1 EeV. In this paper, we present results on the measurement of X max distributions of showers observed over this energy range. Data collected over a period of ∼ 4 years was analyzed for this study. The resulting X max distributions are compared to the Monte Carlo (MC) simulated data distributions for primary cosmic rays with varying composition and a 4-component fit is performed. The comparison and fit are performed for energy bins, of width 0.1 or 0.2 in log 10 (E/eV), spanning the full range of the measured energies. We also examine the mean X max value as a function of energy for cosmic rays with energies greater than 10 15.8 eV. Below 10 17.3 eV, the slope of the mean X max as a function of energy (the elongation rate) for the data is significantly smaller than that of all elements in the models, indicating that the composition is becoming heavier with energy in this energy range. This is consistent with a rigidity-dependent cutoff of events from galactic sources. Finally, an increase in the X max elongation rate is observed at energies just above 10 17 eV indicating another change in the cosmic rays composition.

Motivated by the detection of a significant dipole structure in the arrival directions of ultra-high-energy cosmic rays above 8 EeV reported by the Pierre Auger Observatory (Auger), we search for a large-scale anisotropy using data collected with the surface detector array of the Telescope Array Experiment (TA). With 11 years of TA data, a dipole structure in a projection of the right ascension is fitted with an amplitude of 3.3±1.9% and a phase of 131 • ± 33 •. The corresponding 99% confidence-level upper limit on the amplitude is 7.3%. At the current level of statistics, the fitted result is compatible with both an isotropic distribution and the dipole structure reported by Auger.

SUMMARYIt has been suggested that second to fourth digit ratio (digit ratio) may correlate with male reproductive system function or disorders. This hypothesis is based on finding that the Hox genes control finger development and differentiation of the genital bud during embryogenesis. Thus, we investigated the association between digit ratio and adult testicular volume. A total of 172 Korean men (aged 20-69 years) hospitalized for urological surgery were prospectively enrolled. Patients with conditions known to strongly influence testicular volume were excluded. Before determining testicular volume, the lengths of the second and fourth digits of the right hand were measured by a single investigator using a digital vernier calliper. Using orchidometry, the testes were measured by an experienced urologist who had no information about the patient's digit ratio. To identify the independent predictive factors influencing testicular volume, univariate and multivariate analyses were performed using linear regression models. Age, height, serum testosterone and free testosterone level were not correlated with testicular volume. Digit ratio, along with weight, was significantly correlated with testicular volume (right testicular volume: r = À0.185, p = 0.015; left testicular volume: r = À0.193, p = 0.011; total testicular volume: r = À0.198, p = 0.009). Multivariate analysis using linear regression models showed that only digit ratio was the independent factor to predict all (right, left and total) testicular volumes (right testicular volume: b = À0.174, p = 0.023; left testicular volume: b = À0.181, p = 0.017; total testicular volume: b = À0.185, p = 0.014). Our findings demonstrated that digit ratio is negatively associated with adult testicular volume. This means that men with a higher digit ratio may be more likely to have smaller testis compared to those with a lower digit ratio.

This is the first study to identify a significant association between the IRGM single-nucleotide polymorphism (SNP) rs10065172 and susceptibility to active TB disease in an Asian population. The results suggest that IRGM genetic variants could be associated with susceptibility to active TB disease in the Korean population.