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The status of the research on muon colliders is discussed and plans are outlined for future theoretical and experimental studies. Besides work on the parameters of a 3-4 and 0.5 TeV center-of-mass (COM) energy collider, many studies are now concentrating on a machine near 0.1 TeV (COM) that could be a factory for the s-channel production of Higgs particles. We discuss the research on the various components in such muon colliders, starting from the proton accelerator needed to generate pions from 1098-4402͞99͞2(8)͞081001(73)$15.00 © 1999 The American Physical Society 081001-1 PRST-AB 2 CHARLES M. ANKENBRANDT et al. 081001 (1999) a heavy-Z target and proceeding through the phase rotation and decay (p ! m n m ) channel, muon cooling, acceleration, storage in a collider ring, and the collider detector. We also present theoretical and experimental R&D plans for the next several years that should lead to a better understanding of the design and feasibility issues for all of the components. This report is an update of the progress on the research and development since the feasibility study of muon colliders presented at the Snowmass '96

The differential cross sections for inclusive neutral pions as a function of transverse and longitudinal momentum in the very forward rapidity region have been measured at the Large Hadron Collider (LHC) with the Large Hadron Collider forward detector (LHCf) in proton-proton collisions at √ s = 2.76 and 7 TeV and in proton-lead collisions at nucleon-nucleon center-of-mass energies of √ sNN = 5.02 TeV. Such differential cross sections in proton-proton collisions are compatible with the hypotheses of limiting fragmentation and Feynman scaling. Comparing proton-proton with protonlead collisions, we find a sizable suppression of the production of neutral pions in the differential cross sections after subtraction of ultra-peripheral proton-lead collisions. This suppression corre-arXiv:1507.08764v3 [hep-ex]

The Large Hadron Collider forward (LHCf) experiment is designed to use the LHC to verify the hadronic-interaction models used in cosmic-ray physics. Forward baryon production is one of the crucial points to understand the development of cosmic-ray showers. We report the neutron-energy spectra for LHC √ s = 7 TeV proton-proton collisions with the pseudo-rapidity η ranging from 8.81 to 8.99, from 8.99 to 9.22, and from 10.76 to infinity. The measured energy spectra obtained from the two independent calorimeters of Arm1 and Arm2 show the same characteristic feature before unfolding the difference in the detector responses. We unfolded the measured spectra by using the multidimensional unfolding method based on Bayesian theory, and the unfolded spectra were compared with current hadronic-interaction models. The QGSJET II-03 model predicts a high neutron production rate at the highest pseudo-rapidity range similar to our results and the DPMJET 3.04 model describes our results well at the lower pseudo-rapidity ranges. However no model perfectly explains the experimental results in the whole pseudo-rapidity range. The experimental data indicate the most abundant neutron production rate relative to the photon production, which does not agree with predictions of the models.

The pentasubstituted pyridine natural products harzianopyridone and atpenins are potent inhibitors of mitochondrial complex II. We identified the pathways of these compounds from their fungal producers and uncovered that the biosynthetic steps require multiple iterative enzymes. In particular, a methyltransferase and a flavin-dependent monooxygenase are used iteratively to introduce C5 and C6 methoxy groups. The pathway unexpectedly requires the installation and removal of an N-methoxy group, which is proposed to be a directing group that tunes the reactivity of the pyridone ring, possibly through the alpha effect.