Methacrylate-terminated polypept(o)ides were directly synthesized via NCA-ROP, and then surface-grafted to form a polymer brush coating with infection-resistant efficacy.

3D graphene frameworks/Co O composites are produced by the thermal explosion method, in which the generation of Co O nanoparticles, reduction of graphene oxide, and creation of 3D frameworks are simultaneously completed. The process prevents the agglomeration of Co O particles effectively, resulting in monodispersed Co O nanoparticles scattered on the 3D graphene frameworks evenly. The prepared 3D graphene frameworks/Co O composites used as electrodes for supercapacitor display a definite improvement on electrochemical performance with high specific capacitance (≈1765 F g at a current density of 1 A g ), good rate performance (≈1266 F g at a current density of 20 A g ), and excellent stability (≈93% maintenance of specific capacitance at a constant current density of 10 A g after 5000 cycles). In addition, the composites are also employed as nonenzymatic sensors for the electrochemical detection of glucose, which exhibit high sensitivity (122.16 µA mM cm ) and noteworthy lower detection limit (157 × 10 M, S/N = 3). Therefore, the authors expect that the 3D graphene frameworks/Co O composites described here would possess potential applications as the electrode materials in supercapacitors and nonenzymatic detection of glucose.

No abstract

An efficient and available material for promoting skin regeneration is of great importance for public health, but it remains an elusive goal. Inspired by fetal scarless wound healing, we develop a wearable biomimetic film (WBMF) composed of hyaluronan (HA), vitamin E (VE), dopamine (DA), and βcyclodextrin (β-CD) that mimics the fetal context (FC) and fetal extracellular matrix (ECM) around the wound bed for dermal regeneration. First, the WBMF creates the FC of sterility, hypoxia, persistent moisture, and no secondary insults for wounds as the result of its seamless adhesion to the skin, optimum stress− stretch and high-cycle fatigue resistance matching the anisotropic tension of the skin, and water-triggered self-healing behavior. Thus, the WBMF modulates the early wound situation to minimize inflammatory response. In the meantime, the WBMF mimics the critical biological function of fetal ECM, inducing fibroblast migration, suppressing the overexpression of transforming growth factor β1, and mediating collagen synthesis, distribution, and reestablishment. As a result, the WBMF accelerates wound healing and gains a normal dermal collagen architecture, thereby restoring scarless appearance. Overall, the WBMF provides a new paradigm for promoting skin wound healing and may find broad utility for the field of regenerative medicine.