IFITM protein is the cells first line of antiviral defense that blocks early stages of viral replication; the underlying mechanism might be associated with the proper distribution in cells. The palmitoylation/depalmitoylation cycle can dynamically regulate protein localization, stability, and function.

It is necessary to improve the output power and spectral width of superluminescent diodes (SLDs) simultaneously. In this paper, we show that both the output power and the spectral width of the SLDs based on InAs/GaAs quantum dots (QDs) can be significantly enhanced by direct Si-doping in the QDs. The maximum output power of the Si-doped QD-SLD reaches 20.5 mW at an injection current of 570 mA, while that of the undoped one with an identical structure is only 17.8 mW at the injection current of 550 mA. Moreover, the broadest spectral width of the doped QD-SLD is 105 nm, while that of the undoped QD-SLD is 93 nm. The enhanced performance of the doped QD-SLDs can be attributed to the direct Si doping that leads to inactivating the nonradiative recombination centers within or near the QDs and provides excess carriers to occupy the higher excited states.

Gene introgression from wild species has been shown to be a feasible approach for fiber quality improvement in Upland cotton. Previously, we developed an interspecific G. mustelinum × G. hirsutum advanced-backcross population and mapped over one hundred QTL for fiber quality traits. In the current study, a trait-based selective genotyping approach was utilized to prioritize a small subset of introgression lines with high phenotypic values for different fiber quality traits, to simultaneously validate multiple fiber quality QTL in a single experiment. A total of 75 QTL were detected by CIM and/or single-marker analysis, including 11 significant marker-trait associations (P < 0.001) and three putative associations (P < 0.005) also reported in earlier studies. The QTL that have been validated include three each for fiber length, micronaire, and elongation, and one each for fiber strength and uniformity. Collectively, about 10% of the QTL previously reported have been validated here, indicating that selective genotyping has the potential to validate multiple marker-trait associations for different traits, especially those with a moderate to large-effect detected simultaneously in one experimental population. The G. mustelinum alleles contributed to improved fiber quality for all validated loci. The results from this study will lay the foundation for further fine mapping, marker-assisted selection and map-based gene cloning.