007 Biomorphometric markers for aneurysm rupture in posterior communicating artery aneurysms

Quinn, John C.; He, Wenzhuan; Gandhi, Chirag D.; Romano, Karen; Pendergass, John; Prestigiacomo, Charles J.

doi:10.1136/jnis.2009.000869g

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“…Since the publication of their work, 18 mathematical modelling of aneurysms has been used to understand the biophysical phenomena that contribute to aneurysm growth and rupture. 19 Biomathematical models can incorporate various physical and dynamic phenomena that may provide insight into the potential for aneurysmal rupture and, possibly, help to predict the probability of rupture. 20 The present study describes the biomorphometric properties of aneurysms combined with general clinical data from patients in a prospective clinical series.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Risk of Rupture of Intracranial Aneurysms using Three-Dimensional Cerebral Digital Subtraction Angiography

et al. 2010

J Int Med Res

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The aim of this study was to develop an improved binary logistic regression model for predicting the risk of intracranial aneurysm rupture. A cohort of patients (n=37) with aneurysms underwent three-dimensional digital subtraction angiography examination to measure several morphological parameters of the aneurysm. The aspect ratio (height/neck size) and the size ratio (length/mean diameter of parent vessel) were also calculated. All the morphological parameters combined with the aneurysm location and the patient's baseline data were used to derive a backward binary logistic regression model. In order to validate the model, it was applied to another independent cohort of 19 patients with aneurysms. The model had sensitivity, specificity and accuracy of 84.6%, 66.7% and 78.9%, respectively. This binary logistic regression model of aneurysm rupture risk identified the status of an aneurysm with high accuracy and could form the basis of more complex models in the future.

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Section: Introductionmentioning

confidence: 99%

Assessment of the Risk of Rupture of Intracranial Aneurysms using Three-Dimensional Cerebral Digital Subtraction Angiography

et al. 2010

J Int Med Res

View full text Add to dashboard Cite

show abstract

007 Biomorphometric markers for aneurysm rupture in posterior communicating artery aneurysms

Cited by 1 publication

References 0 publications

Assessment of the Risk of Rupture of Intracranial Aneurysms using Three-Dimensional Cerebral Digital Subtraction Angiography

Assessment of the Risk of Rupture of Intracranial Aneurysms using Three-Dimensional Cerebral Digital Subtraction Angiography

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