“…The clinical value of peripherally inserted central catheters was first recognized for the infusion of antineoplastic agents, antibiotics and parenteral nutrition, all of which potentially benefit from rapid hemodilution or minimized endothelial contact time of irritant solutions and chemicals. Traditionally, PICC lines are inserted in the antecubital fossa of an arm by a specially trained nurse or radiologist (Paul, 2007;Burns, 2005). Procedurally, venipuncture may be accomplished with a standard peripheral catheter and, once venous access is gained, the central catheter is inserted through the peripheral catheter and threaded to a predetermined length based on pre-procedure measurements.…”