061: Time Interval Between the Diagnosis of Cancer in Mothers and Offspring in the Jerusalem Perinatal Study (JPS) Cohort

Paltiel, Ora; Friedlander, Yechiel; Deutsch, Lisa; Yanetz, Rivka; Calderon, Ronit; Tiram, Efrat; Hochner, Hagit; Chana, M.; Harlap, Susan; Manor, Orly

doi:10.1093/aje/161.supplement_1.s16

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“…Among those traced, outcomes studied in offspring over the 24–36 years since their birth include mortality, 24 haematological 77,78 and other 78 malignancies; schizophrenia and other major psychiatric disease; 19,79,80 and cognitive outcomes 75 . In traced mothers, the long‐term studies include malignancies 53,78 and mortality 20 .…”

Section: Resultsmentioning

confidence: 99%

The Jerusalem Perinatal Study cohort, 1964–2005: methods and a review of the main results

Harlap¹,

Davies²,

Deutsch

et al. 2007

Paediatric Perinatal Epid

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SummaryThe Jerusalem Perinatal Study recorded information on population-based cohorts of 92 408 liveand stillbirths in 1964-76, and their parents, with active surveillance of infant deaths and birth defects. Data on maternal conditions, obstetric complications and interventions during labour and delivery were recorded for 92% of the births. Subsets were surveyed with antenatal interviews in 1965-68 (n = 11 467), paediatric admissions to hospital (n = 17 782) and postpartum interviews in 1975-76 (n = 16 912). Data from some offspring were linked to records of a health examination at age 17. The offspring, mothers and fathers have been traced recently, their vital status assessed, and the data linked to Israel's Cancer Registry and Psychiatric Registry. This paper describes the different types of data available, their sources, and some potential biases. Characteristics of this unique population are shown. Findings from the study are reviewed and a list of references is provided. The cohorts provide a unique source of data for a wide variety of studies.

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