Untitled

Positive changes in the continuous desaturation index during mechanical ventilation are associated with mortality due to acute respiratory failure

“…Fifty-eight patients with and without ALI/ARDS were followed during the first 24 hours of MV with the DIMS. The system computes the CDI from the positive end-expiratory pressure (PEEP), the inspired fraction of oxygen (FiO 2 ) and arterial saturation by pulse oximetry (SpO 2 ) [ 1 , 2 ]. The CDI is a percentage that is displayed graphically and numerically.…”

“…We have previously shown that the desaturation index (DI) and the continuous desaturation index (CDI) displayed on the desaturation index monitoring system (DIMS) have a high sensitivity and specificity to identify lung dysfunction [ 1 , 2 ]. However, dynamic changes during mechanical ventilation (MV) that may reflect the patient's response for MV treatment have not yet been tested.…”