1.16 Electrospinning for Membrane Fabrication: Strategies and Applications

Tijing, Leonard D.; Woo, Yun Chul; Yao, Minwei; Ren, Jiawei; Shon, Ho Kyong

doi:10.1016/b978-0-12-409547-2.12262-0

Cited by 39 publications

(26 citation statements)

References 221 publications

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“…For this project, electrospinning was done with a polymer-solvent solution, because this will avoid the early degradation of the bioresorbable polymers and the antiseptic agent due to processing with heat [11]. The residual amount of solvent in the membrane has to be very low to avoid cytotoxic effects [12].…”

Section: Membrane Formulation Designmentioning

confidence: 99%

Electrospun Bioresorbable Membrane Eluting Chlorhexidine for Dental Implants

et al. 2020

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To prevent the uncontrolled development of a pathogenic biofilm around a dental implant, an antimicrobial drug-release electrospun membrane, set up between the implant and the gingival tissue, was developed by taking several technical, industrial and regulatory specifications into account. The membrane formulation is made of a blend of poly(l-lactic–co–gycolic acid) (PLGA, 85:15) and poly(l-lactic acide–co–ɛ-caprolactone) (PLC, 70:30) copolymers with chlorhexidine diacetate (CHX) complexed with β-cyclodextrin (CD). The amount of residual solvent, the mechanical properties and the drug release kinetics were tuned by the copolymers’ ratio, between 30% and 100% of PLC, and a CHX loading up to 20% w/w. The membranes were sterilized by γ-irradiation without significant property changes. The fiber′s diameter was between 600 nm and 3 µm, depending on the membrane composition and the electrospinning parameters. CHX was released in vitro over 10 days and the bacterial inhibitory concentration, 80 µg·mL−1, was reached within eight days. The optimal membrane, PGLA/PLC/CHX-CD (60%/40%/4%), exhibited a breaking strain of 50%, allowing its safe handling. This membrane and a membrane without CHX-CD were implanted subcutaneous in a rat model. The cell penetration remained low. The next step will be to increase the porosity of the membrane to improve the dynamic cell penetration and tissue remodeling.

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Section: Membrane Formulation Designmentioning

confidence: 99%

Electrospun Bioresorbable Membrane Eluting Chlorhexidine for Dental Implants

et al. 2020

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“…interconnected pore structure, and adequate mechanical strength that are desirable for many different applications (e.g., biomedical, energy harvesting, clothing, smart materials, sensors, water and wastewater treatment, etc.) (Tijing et al 2017). The ease of fabrication and functionalization makes it more promising.…”

Section: U N C O R R E C T E D P R O O Fmentioning

confidence: 99%

Nanofibers for Water and Wastewater Treatment: Recent Advances and Developments

Tijing

Yao

Ren

et al. 2018

Energy, Environment, and Sustainability

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Materials of nanofibrous morphology and structure are attractive for solving environmental problems including water-related issues. In recent years, increasing interest is geared on the use of specially designed electrospun nanofibers for water/wastewater treatment applications. The nanofibers can be used in the form of nonwoven structures, as stand-alone membranes, as support layer or as a surface modification layer that enables added functionality to a composite material. Continuous research has been carried out in optimizing the nanofiber membrane design and structure by manipulating material, process and surrounding parameters in the electrospinning process. This chapter highlights the recent advances and developments on the potential and application of electrospun nanofibers for water/ wastewater treatment. Comprehensive discussion is presented here on various designs and structures of nanofibers and their applications to water-related treatment and the future prospects of such materials.

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“…Different research groups have focused on modifying membranes to enhance their efficiency using dual layering and the production of superhydrophobic, omniphobic, and Janus membranes [ 62 , 71 ]. Nanofibers used in MD technology are reported to have improved salt rejection and permeate flux for the desalination process [ 11 ]. However, pristine nanofiber membranes have been reported to suffer from membrane wetting due to lack of hydrophobicity, big pore sizes, and less surface functionalities.…”

Section: Applications Of Electrospun Nanofiber Compositesmentioning

confidence: 99%

“…However, adsorbent materials have aggregation issues and, thus, immobilizing them into a support structure has been considered [ 92 ]. The high surface area of nanofibers make them good candidates for adsorption processes, either as primary adsorbent or as support structure [ 11 ]. However, pristine nanofibers usually lack functional groups for selective adsorption and, thus, many of the nanofiber-based materials for adsorption are surface-modified nanofibers or nanofiber composites.…”

Section: Applications Of Electrospun Nanofiber Compositesmentioning

confidence: 99%

“…The layering and thickness increment leads to formation of a nonwoven or membrane structure and enhances the functionalities of the nanofibers [ 10 ]. Nanofiber membranes are popular where electrical, mechanical, and thermal properties as well as separation processes are required, due to their capacity to play the role as a host to immobilize nanoparticles, as adsorbent material for desired pollutants, in mimicking the extracellular matrix for tissue regeneration, and as electrode for batteries and energy devices [ 9 , 11 ]. They also improve both separation and mechanical characteristics for applications like water purification, desalination [ 12 ], and removal of viruses, bacteria, and toxic metal ions from water.…”

Section: Introductionmentioning

confidence: 99%

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Progress on the Fabrication and Application of Electrospun Nanofiber Composites

et al. 2020

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Nanofibers are one of the most attractive materials in various applications due to their unique properties and promising characteristics for the next generation of materials in the fields of energy, environment, and health. Among the many fabrication methods, electrospinning is one of the most efficient technologies which has brought about remarkable progress in the fabrication of nanofibers with high surface area, high aspect ratio, and porosity features. However, neat nanofibers generally have low mechanical strength, thermal instability, and limited functionalities. Therefore, composite and modified structures of electrospun nanofibers have been developed to improve the advantages of nanofibers and overcome their drawbacks. The combination of electrospinning technology and high-quality nanomaterials via materials science advances as well as new modification techniques have led to the fabrication of composite and modified nanofibers with desired properties for different applications. In this review, we present the recent progress on the fabrication and applications of electrospun nanofiber composites to sketch a progress line for advancements in various categories. Firstly, the different methods for fabrication of composite and modified nanofibers have been investigated. Then, the current innovations of composite nanofibers in environmental, healthcare, and energy fields have been described, and the improvements in each field are explained in detail. The continued growth of composite and modified nanofiber technology reveals its versatile properties that offer alternatives for many of current industrial and domestic issues and applications.

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1.16 Electrospinning for Membrane Fabrication: Strategies and Applications

Cited by 39 publications

References 221 publications

Electrospun Bioresorbable Membrane Eluting Chlorhexidine for Dental Implants

Electrospun Bioresorbable Membrane Eluting Chlorhexidine for Dental Implants

Nanofibers for Water and Wastewater Treatment: Recent Advances and Developments

Progress on the Fabrication and Application of Electrospun Nanofiber Composites

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