1,2,3‐Triarylpropenones as starting materials for 2‐pyridinethiones

Abstract

2-Pyridinethiones 3 are obtained in good yields from 1,2,3-triarylpropenones 2 by treatment with cyanothioacetamide 1. Disulfides 4 result from oxydation of 3. Pyridinethiones 3 undergo methylation at the sulfur atom, leading to (methy1thio)pyridines 5, which can be hydrolized to carboxamides 6. Thien0[2,34]pyridines 7 are obtained from 3 upon reaction with methyl chloroacetate.