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Abstract

The article is devoted to a difficult disease for diagnostic search — inflammatory bowel disease. Both frequent combination of inflammatory bowel disease with extraintestinal manifestations and the possibility of extraintestinal lesions development before the intestinal symptoms determine the practical significance of doctors’ awareness of the management of inflammatory bowel disease with comorbid pathology. The article presents two clinical cases of the onset of non-specific ulcerative colitis with extraintestinal manifestations — gangrenous pyoderma and spondyloarthritis. The diagnostic search conducted allowed finding out in time the reasons for the development of extraintestinal manifestations, to diagnose the diseases, and the prescribed adequate treatment stabilized patients’ condition.