1-(3-Amino-1-benzofuran-2-yl)-2-mesitylethanone

Abstract

Key indicatorsSingle-crystal X-ray study T = 293 K Mean '(C±C) = 0.005 A Ê R factor = 0.054 wR factor = 0.132 Data-to-parameter ratio = 11.9For details of how these key indicators were automatically derived from the article, see

2-Acetyl-3-amino-1-benzofuran

“…The molecule is nearly planar, with atom C1 displaced by 0.249 (2) Å from the mean plane through the benzofuran moiety and atoms O1, N1 and C2 (maximum deviation 0.059 Å for atom C2). In the benzofuran ring system, all the bond lengths agree with values reported in the literature (Arıcı et al, 2004).…”

“…Benzofuran derivatives possess analgesic, antimicrobial, bacteriostatic, bactericidal, fungistatic and fungicidal activities (Hassaneen et al, 2002). Many natural benzofurans have physiological, pharmacological and toxic properties and, as a result, there is continuing interest in their chemical synthesis (Kappe et al, 1997;Arıcı et al, 2004). The title compound, (I), was synthesized by the condensation of 1-chloroacetone with 2-cyanophenol in the presence of K 2 CO 3 .…”

1-(1-Benzofuran-2-yl)-2-chloroethanone

“…In the reported structure the O1-C2 distance is 1.385 (3) Å and it is similar to 1.385 Å found in 2-acetylbenzo(b)furan (Thiruvalluvar et al, 2003). However, the substituted compounds: [2-acetyl-3-(benzoylamino)-1-benzofuran (Ocak Ískeleli et al, 2005), 2-acetyl-3-aminobenzofuran (Bachechi et al, 1988), and 1-(3-amino-1-benzofuran-2-yl)-2-mesitylethanone (Arıcı et al, 2004) reveal somewhat longer bond distances of 1.403-1.411 Å.…”

“…For related literature, see: Arıcı et al (2004); Bachechi et al (1988); Fothergill et al (1977); Gareth (2001); Ocak Ískeleli et al (2005); Narimatsu et al (2003); Tanis et al (2006); Thiruvalluvar et al (2003); Weerawarna et al (1991); Zaidlewicz et al (2005).…”

2-Acetamidobenzonitrile

“…Hydroxybenzonitriles, aminobenzonitriles and their derivatives are important starting materials in the synthesis of some heterocyclic molecules (Radl et al, 2000;Arıcı et al, 2004). Heterocyclic molecules play an important role in pharmaceutical research and development as a result of their desirable physical and chemical properties, and the solid-phase synthetic methodology has been developed for many types of ring systems (Franzen, 2000;Wilson, 2001).…”