1-(3-Cyanophenyl)-3-(2-furoyl)thiourea

Abstract

The title compound, C13H9N3O2S, was synthesized from furoyl isothio­cyanate and 3-amino­benzonitrile in dry acetone. The thio­urea group is in the thio­amide form. The thio­urea fragment makes dihedral angles of 3.91 (16) and 37.83 (12)° with the ketofuran group and the benzene ring, respectively. The mol­ecular geometry is stabilized by N—H⋯O hydrogen bonds. In the crystal structure, centrosymmetrically related mol­ecules are linked by two inter­molecular N—H⋯S hydrogen bonds to form dimers.

N-(2-Furoyl)-N′-(2-pyridyl)thiourea

“…For general background, see: Aly et al (2007); Su et al (2006). For related structures, see: Duque et al (2008); Corrê a et al T = 150 K 0.12 Â 0.08 Â 0.06 mm…”

“…1, was synthesized from furoyl isothiocyanate and 2-aminopyridine in dry acetone. Studies of a number of substituted thioureas, including Nfuroylthioureas, show intramolecular hydrogen bonding between N′H and the furoyl oxygen (Duque et al, 2008;Theodoro et al, 2008;Corrêa et al, 2008). There is also an intermolecular NH hydrogen bond with a sulfur of a neighboring molecule to form a two-dimensional network in these latter thioureas.…”