1,3-Cyclohexadien-1-Als: Synthesis, Reactivity and Bioactivities

Tobal, Ignacio E.; Bautista, Rocío; Díez, David; Garrido, Narciso M.; García‐García, Pilar

doi:10.3390/molecules26061772

Cited by 2 publications

(2 citation statements)

References 99 publications

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“…1,3-Cyclohexadiene and 1-(4-Hydroxy-3-methoxyphenyl) have also been reported to have exhibited antimicrobial effects. 34 Ginger can thus be said to be of medicinal importance, rather than being highly and widely recognised only as a flavouring agent. It could be widely used in mitigating many human and other animal diseases.…”

Section: Discussionmentioning

confidence: 99%

Comparative study: Garlic, ginger and turmeric as natural antimicrobials and bioactives

Oyinlola,

Ogunleye,

Balogun

et al. 2024

S. Afr. J. Sci.

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Biologically active compounds in most spices possess antimicrobial and other important biomedical properties. There have been huge demands for natural immunity boosters (spices and herbs), considering the recent global pandemic and challenges relating to drug-resistant pathogens. This study was designed to compare the efficacy of ginger, garlic and turmeric spices against some pathogenic microorganisms. Aqueous extraction of spices, antimicrobial sensitivity and minimum inhibitory concentration tests were done using standard microbiological methods. Bioactive compounds were estimated using the gas chromatography–mass spectrometry (GC-MS) method. Aqueous extracts of ginger inhibited the growth of all test isolates except Streptococcus pneumoniae, with inhibition zones ranging between 0.9 mm and 13.5 mm. Escherichia coli, S. pneumoniae and Haemophilus influenzae were resistant to turmeric extracts, while the extract of garlic inhibited only four of the test pathogens. Inhibition zones for turmeric ranged between 4.4 mm and 10.9 mm, while those for garlic were between 4.7 mm and 11.5 mm. All the spice extracts did not inhibit microbial growth at 10–40%. An antibiotic spectrum indicated that Bacillus sp. was resistant to all but one, nitrofurantoin, which also inhibited the growth of almost all pathogens, except H. influenzae, with zones ranging between 10.5 mm and 11.6 mm. All test pathogens were resistant to cloxacillin except E. coli (10.6 mm). The major phyto-active compounds present in ginger are 2-Butanone,4-(4-hydroxy-3-methoxyphenyl), 1,3-Cyclohexadiene and 1-(4-Hydroxy-3-methoxyphenyl).

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Section: Discussionmentioning

confidence: 99%

Comparative study: Garlic, ginger and turmeric as natural antimicrobials and bioactives

Oyinlola,

Ogunleye,

Balogun

et al. 2024

S. Afr. J. Sci.

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“…The application areas of metal complexes synthesized from salen compounds are quite wide. There are reactions in which they act as reactants and catalysts such as diels-Alder transformations, alkene epoxidation, electrochemical reduction, nucleic acid modification and hydroxyl addition [17,18].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Tetradentate Schiff Base Ligand Containing 3,4-Diamino Benzophenone and Investigation of Complex Formation with Ni (II), Cu (II) and Co (II) metal ions

Bal

2023

Cumhuriyet Science Journal

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Compound that is a novel tetradentate Schiff base ligand [(3,4-bis(((E)-4-(diethylamino)-2-hydroxybenzylidene)amino)phenyl)(phenyl) methanone] (1), 4-(diethylamino) It was synthesized by the reaction of (3,4-diaminophenyl)(phenyl)methanone with -2-hydroxybenzaldehyde. Complex reactions with Co(II) (1a), Cu(II) (1b) and Ni(II) (1c) metals were prepared based on the obtained Schiff base ligand. The synthesized Schiff base and its Ni(II), Cu(II) and Co(II) complexes were featured using FT-IR, UV-vis, photoluminescence, mass and 1H and 13C-NMR spectroscopy. The characterization processes show that the tetradentate Schiff base compound coordinates with metal ions, oxygen of the hydroxyl group and nitrogen of the azomethine group.

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1,3-Cyclohexadien-1-Als: Synthesis, Reactivity and Bioactivities

Cited by 2 publications

References 99 publications

Comparative study: Garlic, ginger and turmeric as natural antimicrobials and bioactives

Comparative study: Garlic, ginger and turmeric as natural antimicrobials and bioactives

Synthesis and Characterization of Tetradentate Schiff Base Ligand Containing 3,4-Diamino Benzophenone and Investigation of Complex Formation with Ni (II), Cu (II) and Co (II) metal ions

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