1,3-Diketones. Synthesis and properties

Abstract

The review generalizes and analyzes published data on the synthesis and chemical transformations of 1,3-diketones over the past 10-15 years.

Formyl MIDA Boronate: C1 Building Block Enables Straightforward Access to α‐Functionalized Organoboron Derivatives

“…Due to wide application of ynones and 1,3‐dicarbonyl compounds in synthetic organic chemistry, we next aimed at the chemoselective oxidation of α‐hydroxy boronates, which allowed synthesis of boron‐substituted analogues of ynones and β‐dicarbonyl compounds for the first time (Scheme ). Dess–Martin oxidation was adapted for the preparation of 33 – 36 by using the CHCl 3 ‐CH 3 CN (9:1) as the solvent to ensure good solubility of the starting alcohols (conditions A ).…”

Formyl MIDA Boronate: C1 Building Block Enables Straightforward Access to α‐Functionalized Organoboron Derivatives

“…Due to wide application of ynones [43,44] and 1,3-dicarbonyl compounds [45][46][47] in synthetic organic chemistry,wenext aimed at the chemoselective oxidation of a-hydroxy boronates, which allowed synthesis of boron-substituted analogues of ynones and b-dicarbonyl compounds for the first time (Scheme 8). Dess-Martin oxidation was adapted for the preparation of 33-36 by using the CHCl 3 -CH 3 CN (9:1) as the solvent to ensure good solubility of the starting alcohols (conditions A).…”

Crystal structure and Hirshfeld surface analysis of 3-cyano-4-hydroxy-2-(4-methylphenyl)-6-oxo-N-phenyl-4-(thiophen-2-yl)cyclohexane-1-carboxamide 0.04-hydrate

“…The significance of -carbonyl compounds in organic chemistry is difficult to overestimate. They are valuable building blocks in organic synthesis and coordination complexes (Shokova et al, 2015;Ma et al, 2015;Gurbanov et al, 2017Gurbanov et al, , 2018Mittersteiner et al, 2020). Cyclocondensation reactions of -diketones with various reagents mainly lead to the formation of carbocyclic and heterocyclic compounds (Mamedov et al, 2013(Mamedov et al, , 2019Naghiyev et al, 2019;Naghiyev, 2020).…”