1,4,5,6-Tetrahydro-as-triazines. I. Sulfuric Acid Catalyzed Condensation of Nitriles and Hydrazino Alcohols¹

Preparation and biological evaluation of novel acylhydrazide derivatives of 2,3-dichloronaphthoquinone

“…15 Hydrazides have been associated with antibacterial, antifungal, antihelminthic and anticonvulsant activities. [16][17][18][19] In addition to their biological properties, hydrazides are starting materials for a range of potentially bioactive derivatives, such as hydrazones, oxadiazoles, triazoles and pyrazolones. Many pyrimidine nucleosides such as gemcitabine, cytarabine, 5-fluorodeoxyuridine, capecitabine, and decitabine, are clinically used for the treatment of both solid and hematological cancers.…”

Solvent-free synthesis of triazines using N-halosulfonamides

“…[1][2] The variety of interesting properties provides numerous applications for these compounds in medicine and agriculture. 3-5 15 They have also been used in many pharmaceutical applications such as hypertension and inhibition of platelets, metal ions and dyes, 6 antileukemic, 7 potent neuroprotective agents, 8 antiinflammatory, 9 antimalarial, 10 antifungal, 11 antibacterial, 12 anticonvulsant 13 and antiviral 14 compounds. For example, some 7-20 phenylimidazo [1,2-b] [1,2,4]triazine derivatives of the general structure 1 (Fig.…”

Electronic structure investigations of 4-aminophthal hydrazide by UV–visible, NMR spectral studies and HOMO–LUMO analysis by ab initio and DFT calculations

“…The hydrazones derivatives are used for fungicides, and in the treatment such as tuberculosis, leprosy and mental disorders. Biological assessment of fatty hydrazide and the derivatives have been the focus of earlier investigative studies [2,3]. The fatty hrdrazides are further derivatives to obtain new anti bacterial and anti fungal agents.…”