We report on the development of, to the best of our knowledge, the first ultrafast burst-mode laser system operating at a central wavelength of approximately 2 μm, where water absorption and, consequently, the absorption of most biological tissue is very high. The laser comprises a harmonically mode-locked 1-GHz oscillator, which, in turn, seeds a fiber amplifier chain. The amplifier produces 500 ns long bursts containing 500 pulses with 1 GHz intra-burst and 50 kHz inter-burst repetition rates, respectively, at an average power of 1 W, corresponding to 40 nJ pulse and 20 μJ burst energies, respectively. The entire system is built in an all-fiber architecture and implements dispersion management such that output pulses are delivered directly from a single-mode fiber with a duration of 340 fs without requiring any external compression. This gigahertzrepetition-rate system is intended for ablation-cooled laser material removal in the 2 μm wavelength region, which is interesting for laser surgery due to the exceptionally high tissue absorption at this wavelength. Fiber lasers with all-fiber architecture, guiding light through optical fibers to the point of exit from the laser system, continue to attract attention as practical and robust sources for various applications such as material processing, spectroscopy, and metrology, to name a few. Material processing with ultrafast pulses has superb aspects such as minimal collateral damage and high precision with the downsides being slow process speed and the requirement of complex laser systems [1]. The ablation-cooled laser material regime demonstrated recently [2] opened the door to transcending the limited ablation rates and the need for tens to hundreds of microjoules which have been impairing ultrafast laser material processing for industrial usage. In this regime, the repetition rate has to be high enough so that there is insufficient time for the targeted spot size to cool down substantially by heat conduction into the rest (bulk) of the target material by the time the next pulse arrives. As a result, the individual pulse energy ablation threshold is scaled down by several orders of magnitude if the repetition rate is simultaneously increased, while the thermal effects to the bulk of the target are also reduced. Furthermore, the simultaneous reduction of pulse energy and the pulse-to-pulse spacing reduces the plasma shielding effects. This is a breakthrough which opens the door to the simplification of ultrafast lasers built for material processing and, hence, boosts the usage of ultrafast fiber lasers outside the laboratory and, consequently, the proliferation of such lasers.Among the many applications, laser surgery is a promising area for ultrafast laser ablation because it can enable precise cutting with minimal collateral damage and improved after-operation healing process [3]. One can foresee that, with laser systems operating around 2 μm, the ablation cooling regime will take its effect on water-rich soft tissues since laser-tissue interaction is strongly ...