1.P.126 Lipoprotein abnormalities in long-term stable liver and renal transplanted patients. A comparative study

Fernández‐Miranda, Consuelo; Calle, Alberto de la; Morales, José Manuel; Guijarro, Carlos; Aranda, José Luis; Gómez, Teresa; Larumbe, Sagrario; Moreno, E.; Rodicio, J. L.; Palacio, A del

doi:10.1016/s0021-9150(97)88304-9

Cited by 8 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In liver transplant patients 53 as well as in a large cohort of SLE patients, 54 exogenous corticosteroid therapy was independently associated with higher total/LDL-cholesterol levels, suggesting that glucocorticoids do also influence the levels of apolipoprotein B-containing lipoproteins in the clinical setting. Our expression analysis revealed that the decrease in plasma VLDL/LDL levels was probably secondary to a decrease in the expression of MYLIP.…”

Section: Discussionmentioning

confidence: 98%

Adrenal-Specific Scavenger Receptor BI Deficiency Induces Glucocorticoid Insufficiency and Lowers Plasma Very-Low-Density and Low-Density Lipoprotein Levels in Mice

Hoekstra

Sluis

Eck

et al. 2013

ATVB

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 98%

Adrenal-Specific Scavenger Receptor BI Deficiency Induces Glucocorticoid Insufficiency and Lowers Plasma Very-Low-Density and Low-Density Lipoprotein Levels in Mice

Hoekstra

Sluis

Eck

et al. 2013

ATVB

View full text Add to dashboard Cite

“…Because of a HAT he underwent an OLT 22 months after the first procedure, but still he was not able to maintain normal serum cholesterol levels without medical treatment. This can be explained by his genetic predisposition for high-cholesterol uptake or to druginduced hypercholesterolemia, a common feature of immunosuppressive agents (35,36). Although some cases reported normal serum cholesterol levels in the long-term follow-up (37), incomplete control of serum cholesterol remains a concern in most of these patients (38).…”

Section: Discussionmentioning

confidence: 99%

Pediatric Liver Transplantation for Metabolic Liver Disease: Experience at King’s College Hospital

et al. 2009

View full text Add to dashboard Cite

show abstract

“…In a comparative study, the prevalence of hypercholesterolemia in long-term stable renal recipients was far higher (80%) compared with liver recipients (26%), probably because of higher dosing with corticosteroids. 50 Even more striking than the difference in prevalence between the two organ recipient groups, was the height of hypercholesterolemia; mean serum cholesterol levels were 226 and 180 mg/dL, respectively, in the renal and hepatic recipient groups. 50 …”

Section: Hyperlipidemia Prevalence Of Hyperlipidemia In Liver Transplmentioning

confidence: 96%

“…50 Even more striking than the difference in prevalence between the two organ recipient groups, was the height of hypercholesterolemia; mean serum cholesterol levels were 226 and 180 mg/dL, respectively, in the renal and hepatic recipient groups. 50 …”

Section: Hyperlipidemia Prevalence Of Hyperlipidemia In Liver Transplmentioning

confidence: 96%

Long-term management of the liver transplant patient: Diabetes, hyperlipidemia, and obesity

Reuben

2001

Liver Transplantation

115

View full text Add to dashboard Cite

Key Points 1. As long-term survival improves after liver transplantation, cardiovascular complications are emerging as a major cause of late morbidity and mortality. It seems reasonable to correct the potentially reversible cardiovascular risk factors of diabetes, hyperlipidemia, and obesity, in addition to hypertension. 2. The results of liver transplantation in diabetics are acceptable in terms of morbidity, mortality, and prevalence of posttransplant diabetes, but the poor outcomes described in some series suggest that more extensive testing for macro-and microvascular disease may become necessary. T he main aim of liver transplantation, besides the immediate goal of saving life, is to return the patient to productive community living with good quality of life. It is ironic, therefore, that many of the health problems that afflict successful liver transplant recipients long term are those of community living in the developed world, including diabetes mellitus, hyperlipidemia, and obesity. These three metabolic derangements, together with hypertension, constitute adverse cardiovascular risk factors for transplant recipients. The management of diabetes in liver transplant recipients is not substantially different from its management in

show abstract

1.P.126 Lipoprotein abnormalities in long-term stable liver and renal transplanted patients. A comparative study

Cited by 8 publications

References 0 publications

Adrenal-Specific Scavenger Receptor BI Deficiency Induces Glucocorticoid Insufficiency and Lowers Plasma Very-Low-Density and Low-Density Lipoprotein Levels in Mice

Adrenal-Specific Scavenger Receptor BI Deficiency Induces Glucocorticoid Insufficiency and Lowers Plasma Very-Low-Density and Low-Density Lipoprotein Levels in Mice

Pediatric Liver Transplantation for Metabolic Liver Disease: Experience at King’s College Hospital

Long-term management of the liver transplant patient: Diabetes, hyperlipidemia, and obesity

Contact Info

Product

Resources

About