1-(Phenylsulfonyl)-2-[1-(phenylsulfonyl)-2-(3,4,5-trimethoxyphenyl)ethyl]indole

Abstract

The title compound contains an indole ring system with two phenylsulfonyl groups and one 3,4,5-trimethoxyphenyl group as exocyclic substituents. The methoxy groups in the 3,4,5-trimethoxyphenyl moiety are twisted with respect to the plane of the ring. One of the phenylsulfonyl ring systems and the ring of the 3,4,5-trimethoxyphenyl group are nearly perpendicular to the indole ring system, while the other phenylsulfonyl ring system is inclined at an angle of 30 ° to it.

3-[β-(4-Chlorophenyl)-α-(4-methoxyphenyl)vinyl]-2-methyl-1-phenylsulfonyl-1H-indole

“…The S-O, S-C and S-N bond distances of 1.417 (3), 1.738 (4) and 1.658 (2) Å , respectively, agree well with the corresponding bond distances in related structures (Beddoes et al, 1994;Seetharaman & Rajan, 1995). The sum of the angles around N1 (355.9 ) is in the same range as in similar structures (Govindasamy et al, 1997(Govindasamy et al, , 1998.…”

(E)-3-(2-Nitrophenyl)-1-{1-phenylsulfonyl-2-[(phenylsulfonyl)methyl]-1H-indol-3-yl}prop-2-en-1-one

“…The indole moiety, is perpendicular to both the nitro phenyl ring and the phenylsulfonyl ring, bonded to the N atom of the indole ring system with interplanar angles 81.04 11 The molecular dimensions in the title compound are in excellent agreement with the corresponding molecular dimensions reported in closely related compounds (Varghese et al, 1986;Seetharaman & Rajan, 1995). 2 (24) graph-set motif (Bernstein, et al, 1995)…”

“…For the biological activity of sulfonamides and their substituted derivatives, see: Brown (1971). For related structures, see: Seetharaman & Rajan (1995); Varghese et al (1986). For graph-set motifs, see: Bernstein et al (1995).…”

4-[Bis(1H-indol-3-yl)methyl]benzonitrile

“…In the molecular structure, (Fig. 1) the bond lengths (Allen et al, 1987) and and angles are within normal ranges and those in the indole group are in agreement with related structures (Govindasamy et al, 1998;Krishna, Velmurugan, Babu & Perumal, 1999;Krishna, Velmurugan & Shanmuga Sundara, 1999;Seetharaman & Rajan, 1995). The didhedral angles formed by the mean planes of the indole ring systems and the benzene ring are 86.44 (7) and 86.96 (7)°.…”

“…For background and the biological activity of bisindolylalkanes and their derivatives, see: Bell et al (1994). For related structures, see: Govindasamy et al (1998); Krishna, Velmurugan, Babu & Perumal (1999); Krishna, Velmurugan & Shanmuga Sundara (1999); Seetharaman & Rajan (1995). For standard bond-length data, see: Allen et al (1987).…”