1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program

Sardella, Gennaro; Spirito, Alessandro; Sartori, Samantha; Angiolillo, Dominick J.; Vranckx, Pascal; Hernandez, Jose M. De la Torre; Krucoff, Mitchell W.; Bangalore, Sripal; Bhatt, Deepak L.; Campo, Gianluca; Cao, Davide; Chehab, Bassem M.; Choi, James W.; Feng, Yihan; Ge, Junbo; Godfrey, Katherine; Hermiller, James; Kunadian, Vijay; Makkar, Raj R.; Maksoud, Aziz; Neumann, Franz-Josef; Picon, Hector; Saito, Shigeru; Thiele, Holger; Toelg, Ralph; Varenne, Olivier; Vogel, Birgit; Zhou, Yujie; Valgimigli, Marco; Windecker, Stephan; Mehran, Roxana

doi:10.1016/j.amjcard.2023.12.049

The American Journal of Cardiology

2024

DOI: 10.1016/j.amjcard.2023.12.049

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1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program

Gennaro Sardella,

Alessandro Spirito,

Samantha Sartori

et al.

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Cited by 3 publications

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Does Age Have a Differential Effect on 1 Month Versus 3 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients at High Bleeding Risk?

Elkaryoni,

Garg,

Abbott

2024

The American Journal of Cardiology

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Does Age Have a Differential Effect on 1 Month Versus 3 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients at High Bleeding Risk?

Elkaryoni,

Garg,

Abbott

2024

The American Journal of Cardiology

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Double Trouble: Dual Antiplatelet Therapy Duration Dilemma in Chronic Kidney Disease Patients With High Bleeding Risk

Paul

2024

The American Journal of Cardiology

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Antiplatelet Therapy for Elderly Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Fioretti,

Sperandeo,

Gerardi

et al. 2024

JCM

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The elderly represent an increasing proportion of patients presenting with acute coronary syndrome (ACS). Various data have shown that the benefits of percutaneous coronary revascularization are maintained in elderly patients presenting with ACS. Conversely, the management of antiplatelet therapy remains challenging and controversial, because older patients are usually at a high risk of both ischemia and bleeding. Moreover, the recommended ischemic and bleeding risk scores in patients with ACS were developed from studies with a low representation of older patients. New antiplatelet strategies have been developed, but their evidence in elderly patients is limited because they are usually underrepresented in randomized clinical trials due to their clinical complexity. The aim of this review is to summarize the different factors associated with increased ischemic and/or bleeding risk and the scientific evidence about the different antiplatelet strategies in elderly patients presenting with ACS and undergoing percutaneous coronary revascularization.

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1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program

Cited by 3 publications

References 28 publications

Does Age Have a Differential Effect on 1 Month Versus 3 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients at High Bleeding Risk?

Does Age Have a Differential Effect on 1 Month Versus 3 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients at High Bleeding Risk?

Double Trouble: Dual Antiplatelet Therapy Duration Dilemma in Chronic Kidney Disease Patients With High Bleeding Risk

Antiplatelet Therapy for Elderly Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

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