1 year mortality after hip fracture in an Irish urban trauma centre

Ferris, Helena; Merron, Georgia; Coughlan, Tara

doi:10.1186/s12891-023-06605-5

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…Kim et al [ 30 ] also found that age over 80 years was a predictor of 1-year mortality. Ferris et al [ 8 ] found that male sex significantly predicted increased mortality, while other authors found that sex has no effect on mortality [ 29 , 30 ]. In the present study, age was a significant predictor of 1-year mortality, but sex was not.…”

Section: Discussionmentioning

confidence: 99%

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One-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China

Hao,

Wang,

Chen

et al. 2024

BMC Geriatr

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Background The accelerated growth of older individuals worldwide has increased the number of patients presenting with fragility hip fractures. Having a hip fracture can cause excess mortality, and patients with hip fracture have a higher risk of death than those without hip fracture. Most studies have treated hip fracture as a single, homogeneous condition, but hip fracture includes two major anatomic types: intertrochanteric fracture and femoral neck fracture. Few studies have specifically evaluated 1-year mortality risk in older individuals with femoral intertrochanteric fracture. The aim of this study was to evaluate 1-year mortality and factors associated with mortality in older individuals with femoral intertrochanteric fracture. Methods A retrospective review was conducted of 563 patients ≥ 65 years old who underwent surgery for femoral intertrochanteric fractures at our institution between January 2010 and August 2018. Patient demographics, comorbidities, and treatment were collected by retrospective chart review. Age, sex, Body Mass Index (BMI), American Society of Anesthesiologists (ASA) classification, Charlson comorbidity index (CCI), Arbeitsgemeinschaft Für Osteosynthesefragen (AO) fracture classification, haemoglobin value at admission, time to surgery, operation time, and intraoperative blood loss were risk factors to be tested. Multivariable logistic regression was used to evaluate associations between variables and death. Results Among the 563 patients, 49 died within 1 year after surgery, and the 1-year mortality rate was 8.7%. Multivariate analysis identified age > 80 years (OR = 4.038, P = 0.011), haemoglobin < 100 g/l (OR = 2.732, P = 0.002), ASA score ≥ 3 (OR = 2.551, P = 0.005), CCI ≥ 3 (OR = 18.412, P = 0.018) and time to surgery > 14 d (OR = 3.907, P = 0.030) as independent risk factors for 1-year mortality. Comorbidities such as myocardial infarction and chronic pulmonary disease were associated with 1-year mortality after adjusting for age > 80 years and time to surgery > 14 days. Conclusions Patients over 80 years old with haemoglobin < 100 g/l, ASA score ≥ 3, CCI ≥ 3, and multiple comorbidities, especially myocardial infarction and chronic pulmonary disease before surgery, are at a higher risk of 1-year mortality. Doctors should pay more attention to these vulnerable patients, and a surgical delay greater than 14 days should be avoided.

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Section: Discussionmentioning

confidence: 99%

“…Many studies [ 4 – 6 ] on hip fractures have described high mortality rates. Most studies document an increase in mortality lasting for 6 to 12 months [ 7 , 8 ]. Identifying predictors of 1-year mortality could help discriminate between those at higher risk of adverse outcomes and facilitate targeted interventions [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

One-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China

Hao,

Wang,

Chen

et al. 2024

BMC Geriatr

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“…Many studies have shown that hip fractures represent a remarkable burden to health care systems and societies worldwide, and that patients with hip fracture incur a substantial rise in direct care costs and secondary costs (for specific services and treatments), and have a higher mortality rate than their counterparts [ 7 , 8 , 9 ]. Recent studies suggest a mortality rate of 17% to 25% within 1 year following hip fracture or surgery in older adults [ 10 , 11 ]. Furthermore, frequent consequences of hip fracture due to falls in older people include reduced functions and abilities (for walking and for basic activities of independent daily living), and compromised quality of life [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of Hip Fractures Due to Falls

Ilic,

Ristic,

Stojadinovic

et al. 2023

Medicina

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Background and Objectives: The epidemiological pattern of the hip fracture burden attributable to falls in Central European countries is still insufficiently known. The aim of this study was to assess the regional and national trends of hip fractures due to falls in Central Europe from 1990 to 2019. Materials and Methods: Using the Global Burden of Disease (GBD) 2019 study, this descriptive epidemiological study presents trends in incidence of and Years Lived with Disability (YLDs) from hip fractures due to falls in the region of Central Europe. All estimates (age- and sex-specific rates, and age-standardized rates) were expressed per 100,000. A joinpoint regression analysis was used to assess trends: the average annual percent change (AAPC) with a corresponding 95% confidence interval (95% CI) was calculated. Results: Among all new cases of hip fracture in the population as a whole in Central Europe in 2019, 3.9% in males and 7.0% in females were attributable to falls, while the share of hip fractures due to falls in the population aged 70 and over was 16.9% in males and 20.0% in females. About 400,000 new cases of hip fracture due to falls occurred in the Central European region in 2019 (220,000 among males and 160,000 among females), resulting in 55,000 YLDs (32,000 in females and 22,000 in males). About one-third of all new cases (59,326 in males and 72,790 in females) and YLDs (8585 in males, and 10,622 in females) of hip fractures due to falls were recorded in Poland. From 1990 to 2019, the age-standardized incidence rates of hip fracture due to falls showed a decreasing tendency in females (AAPC = −1.1%), and an increasing tendency in males (AAPC = 0.1%). Both in males and females, YLDs rates of hip fracture due to falls in the Central European region decreased (AAPC = −1.6% and AAPC = −2.4%, respectively). Conclusions: Hip fracture due to falls represents an important health issue in the Central European region, although incidences and YLDs declined in the most recent decades. However, further efforts to reduce the burden of hip fractures attributed to falls are needed.

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Impact of hematologic inflammatory markers on the prognosis of geriatric hip fracture: a systematic review and meta-analysis

Pan,

Chou,

et al. 2024

Eur J Med Res

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Background Geriatric hip fractures pose a significant health burden, and inflammation may play a role in the short- and long-term prognosis. However, the prognostic significance of hematologic inflammatory markers in geriatric patients with fractures is not understood. The aim of this systematic review and meta-analysis was to assess the prognostic implications of systemic inflammatory markers on the long-term mortality of older patients with hip fractures. Methods PubMed, EMBASE, and Cochrane CENTRAL were searched from inception to December 19, 2023. Prospective, retrospective cohort, and case–control studies investigating the prognostic impact of hematologic inflammatory markers on mortality after hip fracture were eligible. Pooled hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) were calculated to determine the associations between the markers and mortality risk, with heterogeneity assessed by I 2 statistic. The quality of the studies was appraised using the Newcastle–Ottawa Scale. Results Ultimately, 7 retrospective studies involving a total of 7212 patients were included. The meta-analysis revealed that the neutrophil-to-lymphocyte ratio (NLR) (HR = 1.04, 95% CI 1.02–1.08), systemic immune–inflammatory index (SII) (HR = 1.03, 95% CI 1.01–1.05), and red cell distribution width (RDW) (HR = 1.07, 95% CI 1.01–1.14) independently correlated with increased long-term mortality. Conclusions Elevated NLR, SII, and RDW are independently associated with increased long-term mortality in older patients with hip fractures. These findings imply the potential value of incorporating these inflammatory indicators to aid in prognostic stratification of geriatric patients with hip fractures.

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1 year mortality after hip fracture in an Irish urban trauma centre

Cited by 4 publications

References 24 publications

One-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China

One-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China

Epidemiology of Hip Fractures Due to Falls

Impact of hematologic inflammatory markers on the prognosis of geriatric hip fracture: a systematic review and meta-analysis

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