10-(4-Bromophenyl)-9-(4-methoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7-tetrahydroacridine-1,8(2H,5H,9H,10H)-dione

Abstract

The crystal structure of the title compound, C30H32BrNO3, is stabilized by two C—H...O intermolecular hydrogen bonds and one weak C—H...π interaction. C—H...O hydrogen bonds generate C(10) chains and an R22(16) ring motif. In the title compound, the central pyridine ring in the acridinedione system is approximately planar while the outer two rings adopt half‐chair conformations. The buckling angle between the two halves [at the N...C(PhOMe) line] of 6.94 (2)° shows the degree of planarity of the acridinedione system. The dihedral angle between the planes of the two aromatic rings is 9.66 (2)°.

Synthesis and antimicrobial activities of novel bisacridine-1,8-dione derivatives

“…They have similarities in structure to the biologically important compounds NADH and NADPH (Singh et al, 1982;Odabasoglu et al, 2007;Srividya et al, 1996).…”